Evidence map›Paper›PMID 37568935›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Addressing Challenges of Opportunistic Computed Tomography Bone Mineral Density Analysis.

Kirsten N Bott, Bryn E Matheson, Ainsley C J Smith, Justin J Tse, Steven K Boyd, Sarah L Manske

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kirsten N BottDepartment of Radiology, University of Calgary, Calgary, AB T2N 1N4, Canada.
Bryn E MathesonMcCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB T2N 4Z6, Canada.
Ainsley C J SmithDepartment of Radiology, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0002-9604-6382
Justin J TseDepartment of Radiology, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0002-5107-5884
Steven K BoydDepartment of Radiology, University of Calgary, Calgary, AB T2N 1N4, Canada.
Sarah L ManskeDepartment of Radiology, University of Calgary, Calgary, AB T2N 1N4, Canada.
University of Calgary · CA

Funding

Arthritis Society STAR-18-0189Natural Sciences and Engineering Research Council DG 2018-03908Natural Sciences and Engineering Research Council RGPIN-2019-04135
6 · The paper itself

Abstract

Computed tomography (CT) offers advanced biomedical imaging of the body and is broadly utilized for clinical diagnosis. Traditionally, clinical CT scans have not been used for volumetric bone mineral density (vBMD) assessment; however, computational advances can now leverage clinically obtained CT data for the secondary analysis of bone, known as opportunistic CT analysis. Initial applications focused on using clinically acquired CT scans for secondary osteoporosis screening, but opportunistic CT analysis can also be applied to answer research questions related to vBMD changes in response to various disease states. There are several considerations for opportunistic CT analysis, including scan acquisition, contrast enhancement, the internal calibration technique, and bone segmentation, but there remains no consensus on applying these methods. These factors may influence vBMD measures and therefore the robustness of the opportunistic CT analysis. Further research and standardization efforts are needed to establish a consensus and optimize the application of opportunistic CT analysis for accurate and reliable assessment of vBMD in clinical and research settings. This review summarizes the current state of opportunistic CT analysis, highlighting its potential and addressing the associated challenges.

Indexed as

computed tomographyinternal BMD calibrationopportunistic analysis

Identifiers

PMID37568935
PMCPMC10416827
OpenAlexW4385490787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.