Evidence map›Paper›PMID 37568871›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Heart-Rate-to-Blood-Pressure Ratios Correlate with Malignant Brain Edema and One-Month Death in Large Hemispheric Infarction: A Cohort Study.

Xindi Song, Yanan Wang, Wen Guo, Meng Liu, Yilun Deng, Kaili Ye, Ming Liu

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Time-varying association between blood pressure and malignant brain edema after large hemispheric infarction: a prospective cohort study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xindi SongDepartment of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0003-3718-335X
Yanan WangDepartment of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.
Wen GuoDepartment of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.
Meng LiuDepartment of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.
Yilun DengDepartment of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.
Kaili YeDepartment of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.
Ming LiuDepartment of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.
Sichuan University · CN

Funding

1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University ZYGD18009National Natural Science Foundation of China 81974181
6 · The paper itself

Abstract

introductionLarge hemispheric infarction (LHI) can lead to fatal complications such as malignant brain edema (MBE). We aimed to investigate the correlation between heart-rate-to-blood-pressure ratios and MBE or one-month death after LHI.

methodsWe prospectively included LHI patients from a registered cohort. Hourly heart-rate-to-blood-pressure ratios were recorded as a variation of the traditional shock index (SI), SI

resultsOf the included 162 LHI patients, 28.4% (46/162) developed MBE and 25.3% (40/158) died within one month. SI

conclusionsHigher and more fluctuated heart-rate-to-blood-pressure ratios independently correlated with MBE development and one-month death in LHI patients, especially during the second 12 h (13-24 h) epoch after onset.

Indexed as

biomarkersblood pressureheart ratemalignant brain edemashock index

Identifiers

PMID37568871
PMCPMC10416946
OpenAlexW4385348820

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.