Evidence map›Paper›PMID 37568826›Full record

ReviewCancers2023

Maintenance Chemotherapy for Patients with Rhabdomyosarcoma.

Gianni Bisogno, Veronique Minard-Colin, Meriel Jenney, Andrea Ferrari, Julia Chisholm, Daniela Di Carlo, Lisa Lyngsie Hjalgrim, Daniel Orbach, Johannes Hendrikus Maria Merks, Michela Casanova

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 5 countries.

Gianni BisognoDepartment of Women's and Children's Health, University of Padua, 35128 Padua, Italy.ORCID 0000-0003-4462-5523
Veronique Minard-ColinDepartment of Pediatric and Adolescent Oncology, Institut Gustave-Roussy, Université Paris-Saclay, 94800 Villejuif, France.
Meriel JenneyDepartment of Paediatric Oncology, Children's Hospital for Wales, Heath Park, Cardiff CF14 4XW, UK.
Andrea FerrariPediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, 20133 Milan, Italy.ORCID 0000-0002-4724-0517
Julia ChisholmChildren and Young People's Unit, Royal Marsden Hospital and Institute of Cancer Research, Sutton SM2 5PT, UK.ORCID 0000-0003-3479-7997
Daniela Di CarloDepartment of Women's and Children's Health, University of Padua, 35128 Padua, Italy.ORCID 0000-0003-0573-8576
Lisa Lyngsie HjalgrimDepartment of Paediatric and Adolescent Medicine, University Hospital Copenhagen, 2100 Copenhagen, Denmark.ORCID 0000-0001-5186-3365
Daniel OrbachSIREDO Oncology Centre (Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer), Institut Curie, Paris Sciences et Lettres L University, 75005 Paris, France.ORCID 0000-0002-2520-139X
Johannes Hendrikus Maria MerksPrincess Máxima Centre for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.ORCID 0000-0001-7659-1028
Michela CasanovaPediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, 20133 Milan, Italy.
Fondazione IRCCS Istituto Nazionale dei Tumori · ITUniversity of Padua · ITCopenhagen University Hospital · DKInstitut Curie · FRNoah's Ark Children's Hospital for Wales · GBRoyal Marsden NHS Foundation Trust · GBUniversité Paris-Saclay · FRUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maintenance chemotherapy (MC) defines the administration of prolonged relatively low-intensity chemotherapy with the aim of "maintaining" tumor complete remission. This paper aims to report an update of the RMS2005 trial, which demonstrated better survival for patients with high-risk localized rhabdomyosarcoma (RMS) when MC with vinorelbine and low-dose cyclophosphamide was added to standard chemotherapy, and to discuss the published experience on MC in RMS. In the RMS2005 study, the outcome for patients receiving MC vs. those who stopped the treatment remains superior, with a 5-year disease-free survival of 78.1% vs. 70.1% (

Indexed as

low-dose chemotherapymaintenance chemotherapymetronomic chemotherapyrhabdomyosarcoma

Identifiers

PMID37568826
PMCPMC10417571
OpenAlexW4385654774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.