Evidence map›Paper›PMID 37568792›Full record

ArticleCancers2023

Reduced Racial Disparity as a Result of Survival Improvement in Prostate Cancer.

Baoyi Zhang, Jianrong Li, Mabel Tang, Chao Cheng

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Baoyi ZhangDepartment of Chemical and Biomolecular Engineering, Rice University, Houston, TX 77030, USA.
Jianrong LiDepartment of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Mabel TangDepartment of Biosciences, Rice University, Houston, TX 77030, USA.ORCID 0000-0002-5932-7089
Chao ChengDepartment of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-5002-3417

Funding

Computational Identification of new candidate drugs for lung cancer treatmentR21CA227996 · NCI · BAYLOR COLLEGE OF MEDICINE · PI CHENG, CHAO, ONEGA, TRACY · 2019 to 2020
$397k
NCI NIH HHS 1R21CA227996NCI NIH HHS R21 CA227996
6 · The paper itself

Abstract

Prostate cancer is a cancer type associated with a high level of racial and socioeconomic disparities as reported by many previous studies. However, the changes in these disparities in the past two decades have not been systematically studied. In this study, we investigated the Surveillance Epidemiology End Results (SEER) data for prostate cancer patients diagnosed during 2004-2018. African Americans and Asians showed significantly better and worse cancer-specific survival (CSS), respectively, compared to non-Hispanic white individuals after adjusting for confounding factors such as age and cancer stage. Importantly, the data indicated that racial disparities fluctuated and reached the highest level during 2009-2013, and thereafter, it showed a substantial improvement. Such a change cannot be explained by the improvement in early diagnosis but is mainly driven by the differential improvement in CSS between races. Compared with Asians and non-Hispanic whites, African American patients achieved a more significant survival improvement during 2014-2018, while no significant improvement was observed for Hispanics. In addition, the SEER data showed that high-income patients had significantly longer CSS than low-income patients. Such a socioeconomic disparity was continuously increasing during 2004-2018, which was caused by the increased survival benefits of the high-income patients with respect to the low-income patients. Our study suggests that more efforts and resources should be allocated to improve the treatment of patients with low socioeconomic status.

Indexed as

prognosisprostate cancerracial disparitysocioeconomic disparity

Identifiers

PMID37568792
PMCPMC10417437

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.