Evidence map›Paper›PMID 37568767›Full record

ArticleCancers2023

Evaluation of CIN2/3 Lesion Regression in GynTect

Heike Hoyer, Claudia Stolte, Gerd Böhmer, Monika Hampl, Ingke Hagemann, Elisabeth Maier, Agnieszka Denecke, Christine Hirchenhain, Jan Patzke, Matthias Jentschke and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Epigenetic Biomarkers for Cervical Cancer Progression: A Scoping Review.International journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Accuracy of GynTectCancers · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 1 country.

Heike HoyerInstitut für Medizinische Statistik, Informatik und Datenwissenschaften, Universitätsklinikum Jena, 07743 Jena, Germany.
Claudia StolteInstitut für Zytologie und Dysplasie (IZD), 30159 Hannover, Germany.
Gerd BöhmerInstitut für Zytologie und Dysplasie (IZD), 30159 Hannover, Germany.
Monika HamplFrauenklinik, Universitätsklinikum Düsseldorf, 40225 Düsseldorf, Germany.
Ingke HagemannAbts+Partner Partnerschaftsgesellschaft, 24103 Kiel, Germany.ORCID 0000-0001-6383-2697
Elisabeth MaierPraxis Dr. Elisabeth Maier, 80796 München, Germany.
Agnieszka DeneckeKlinikum Wolfsburg, 38440 Wolfsburg, Germany.
Christine HirchenhainKlinik und Poliklinik für Frauenheilkunde und Geburtshilfe, Technische Universität Dresden, 01307 Dresden, Germany.
Jan PatzkeCytoConcept, 44145 Dortmund, Germany.
Matthias JentschkeKlinik für Frauenheilkunde und Geburtshilfe, Medizinische Hochschule Hannover (MHH), 30625 Hannover, Germany.ORCID 0000-0001-7613-1531
Axel GerickPraxis Dr. Axel Gerick, 52072 Aachen, Germany.
Tabitha HellerZentrum für Klinische Studien (ZKS), Universitätsklinikum Jena, 07747 Jena, Germany.
Juliane HippeOngnostics GmbH, 07749 Jena, Germany.
Kristina WunschOngnostics GmbH, 07749 Jena, Germany.
Martina SchmitzOngnostics GmbH, 07749 Jena, Germany.ORCID 0000-0003-2430-3500
Matthias DürstKlinik und Poliklinik für Frauenheilkunde und Fortpflanzungsmedizin, Universitätsklinikum Jena, 07747 Jena, Germany.ORCID 0000-0003-1235-1150
oncgnostics (Germany) · DEJena University Hospital · DEOrthopädische Praxis · DEDüsseldorf University Hospital · DEFraunhofer Project Centre Wolfsburg · DEKlinik für Frauenheilkunde · DEKlinik und Poliklinik für Frauenheilkunde und Fortpflanzungsmedizin · DEMedizinische Hochschule Hannover · DE

Funding

Intramural funds granted to MD and funds received by oncgnostics GmbH, Jena 01-2022
6 · The paper itself

Abstract

Cervical intraepithelial neoplasia (CIN) grade 2/3 has a high spontaneous regression rate, especially among women ≤29 years of age. To reduce overtreatment, reliable prognostic biomarkers would be helpful. The main aim of this study was to analyze the negative predictive value of the methylation marker panel GynTect

Indexed as

cervical precancersCINmethylation markerspredictive markersregressionwatchful waiting

Identifiers

PMID37568767
PMCPMC10417134
OpenAlexW4385555857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.