Evidence map›Paper›PMID 37568698›Full record

ArticleCancers2023

Relationships among Inflammatory Biomarkers and Objectively Assessed Physical Activity and Sleep during and after Chemotherapy for Gynecologic Malignancies.

Danielle B Tometich, Aasha I Hoogland, Brent J Small, Michelle C Janelsins, Crystal Bryant, Yvelise Rodriguez, Brian D Gonzalez, Xiaoyin Li, Hailey W Bulls, Brian W James and 12 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 6 institutions in 1 country.

Danielle B TometichDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.ORCID 0000-0002-5939-0635
Aasha I HooglandDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.ORCID 0000-0002-8691-8132
Brent J SmallSchool of Aging Studies, University of South Florida, Tampa, FL 33620, USA.
Michelle C JanelsinsDepartment of Surgery and Neuroscience, University of Rochester Medical Center, Rochester, NY 14642, USA.
Crystal BryantDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
Yvelise RodriguezDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.
Brian D GonzalezDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.ORCID 0000-0001-5108-5735
Xiaoyin LiDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.ORCID 0000-0001-8028-8910
Hailey W BullsSection of Palliative Care and Medical Ethics, Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Brian W JamesMorsani College of Medicine, University of South Florida, Tampa, FL 33620, USA.
Bianca ArboledaMorsani College of Medicine, University of South Florida, Tampa, FL 33620, USA.
Claudia Colon-EchevarriaDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL 33612, USA.ORCID 0000-0003-0157-8261
Mary K TownsendDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Shelley S TworogerDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Paulo RodriguezDepartment of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Laura B OswaldDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.ORCID 0000-0001-6281-2512
Julienne E BowerDepartment of Psychology, University of California Los Angeles, Los Angeles, CA 90095, USA.
Sachin M ApteHuntsman Cancer Institute, Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT 84112, USA.
Robert M WenhamDepartment of Gynecologic Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Hye Sook ChonDepartment of Gynecologic Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Mian M ShahzadDepartment of Gynecologic Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Heather S L JimDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL 33612, USA.ORCID 0000-0001-7353-3711
Moffitt Cancer Center · USUniversity of South Florida · USUniversity of California, Los Angeles · USUniversity of Pittsburgh · USUniversity of Rochester Medical Center · USUniversity of Utah · US

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Using MC1R genotype to impact skin cancer risk behaviors in Hispanics/LatinosU54CA163068 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI Shannon Marie Christy · 2012 to 2026
$23.1M
Using MC1R genotype to impact skin cancer risk behaviors in Hispanics/LatinosU54CA163071 · NCI · PONCE SCHOOL OF MEDICINE · PI Harold I Saavedra · 2012 to 2026
$23.0M
Project 4P01CA250984 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI STEWART, PAUL ALLEN · 2021 to 2025
$10.1M
Sickness Behaviors in Gynecologic Cancer Patients Treated with ChemotherapyR01CA164109 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI JIM, HEATHER S.L. · 2012 to 2016
$2.5M
Plant-derived extracts regulate immunosuppressive myelopoiesis in Breast cancer patientsR01CA262121 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI RODRIGUEZ, PAULO CESAR · 2021 to 2025
$2.1M
Functional reprogramming of tumor-MDSC through antibody-based therapies targeting Notch ligandsR01CA233512 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI RODRIGUEZ, PAULO CESAR · 2019 to 2023
$2.0M
Mitochondrial stress promotes immunosuppressive potential of myeloid subsets in tumorsR01CA273034 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI RODRIGUEZ, PAULO CESAR · 2022 to 2025
$1.9M
Development and piloting of an intervention to reduce the impact of opioid stigma in cancer painK08CA263317 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Hailey Waddell Bulls · 2022 to 2026
$729k
Cancer-related cognitive impairment: Real-time evaluation and assessment of long-term impact of treatment on young adult survivors (CRCI REALITY)K99CA270294 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI TOMETICH, DANIELLE · 2022 to 2023
$220k
NCI NIH HHS K08 CA263317NCI NIH HHS K08CA263317NCI NIH HHS K99 CA270294NCI NIH HHS K99CA279294NCI NIH HHS P01 CA250984NCI NIH HHS P30 CA076292NCI NIH HHS P30CA076292NCI NIH HHS R01 CA164109NCI NIH HHS R01CA164109NCI NIH HHS R01 CA233512NCI NIH HHS R01 CA262121NCI NIH HHS R01 CA273034NCI NIH HHS U54 CA163068NCI NIH HHS U54CA163068NCI NIH HHS U54 CA163071NCI NIH HHS U54CA163071NCI NIH HHS UG1 CA189961
6 · The paper itself

Abstract

Little is known regarding associations between inflammatory biomarkers and objectively measured physical activity and sleep during and after chemotherapy for gynecologic cancer; thus, we conducted a longitudinal study to address this gap. Women with gynecologic cancer (patients) and non-cancer controls (controls) completed assessments before chemotherapy cycles 1, 3, and 6 (controls assessed contemporaneously), as well as at 6- and 12-month follow-ups. Physical activity and sleep were measured using wrist-worn actigraphs and sleep diaries, and blood was drawn to quantify circulating levels of inflammatory markers. Linear and quadratic random-effects mixed models and random-effects fluctuation mixed models were used to examine physical activity and sleep over time, as well as the associations with inflammatory biomarkers. On average, patients (

Indexed as

gynecologic cancerinflammationphysical activitysleep

Identifiers

PMID37568698
PMCPMC10416903
OpenAlexW4385421675

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.