Evidence map›Paper›PMID 37568619›Full record

ArticleCancers2023

Mucinous and Signet-Ring Cell Colonic Adenocarcinoma in Inflammatory Bowel Disease: A Case-Control Study.

Benedetto Neri, Roberto Mancone, Luca Savino, Sara Schiavone, Vincenzo Formica, Francesca Pizzi, Silvia Salvatori, Michelangela Mossa, Stefano Migliozzi, Mariasofia Fiorillo and 7 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Clinicopathological and molecular landscape in colorectal cancer associated with colorectal polyps and inflammatory bowel disease.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Benedetto NeriGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.ORCID 0000-0002-0803-7903
Roberto ManconeGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.
Luca SavinoPathology Unit, Department of Biomedicine and Prevention, University "Tor Vergata" of Rome, 00133 Roma, Italy.
Sara SchiavoneGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.
Vincenzo FormicaMedical Oncology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.ORCID 0000-0002-5380-3144
Francesca PizziGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.
Silvia SalvatoriGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.ORCID 0000-0002-4980-6289
Michelangela MossaGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.ORCID 0000-0001-5013-7484
Stefano MigliozziGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.
Mariasofia FiorilloGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.
Cristina MorelliMedical Oncology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.
Alessandro MoscardelliGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.ORCID 0009-0006-7913-5320
Elisabetta LolliGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.
Emma CalabreseGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.
Giuseppe S SicaDepartment of Surgery, University "Tor Vergata" of Rome, 00133 Roma, Italy.
Giovanni MonteleoneGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.ORCID 0000-0003-1339-9076
Livia BianconeGastroenterology Unit, Department of Systems Medicine, University "Tor Vergata" of Rome, 00133 Roma, Italy.ORCID 0000-0002-9056-1957
University of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A higher frequency of mucinous and signet-ring cell colonic adenocarcinoma has been reported in inflammatory bowel disease (IBD). The primary aim was to investigate the frequency of mucinous and signet-ring cell colorectal adenocarcinoma in patients with IBD (Cases) versus age-matched non-IBD Controls. The secondary aims were to compare the characteristics of these two histotypes of colorectal cancer (CRC) in IBD patients vs. Controls and to search for specific risk factors in IBD. In a case-control study, all IBD patients with CRC diagnosed from 2000 to 2022 were enrolled and matched for age (1:2) with non-IBD Controls with CRC. The study population included 120 CRC patients (40 IBD, 80 Controls). In IBD, CRC included standard adenocarcinoma in 23 (57.5%) patients mucinous/signet-ring cell adenocarcinoma in 17 (42.5%) patients. The proportion of mucinous/signet-ring cell adenocarcinoma was higher in IBD than in Controls (17 [42.5%] vs. 18 [22.5%];

Indexed as

colorectal cancerinflammatory bowel diseasemucinous adenocarcinomasignet-ring cell adenocarcinoma

Identifiers

PMID37568619
PMCPMC10417294
OpenAlexW4385308284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.