Evidence map›Paper›PMID 37568544›Full record

ArticleJournal of clinical medicine2023

Global Epidemiology and Burden of Elderly-Onset Inflammatory Bowel Disease: A Decade in Review.

Pojsakorn Danpanichkul, Kanokphong Suparan, Suchapa Arayakarnkul, Aunchalee Jaroenlapnopparat, Natchaya Polpichai, Panisara Fangsaard, Siwanart Kongarin, Karan Srisurapanont, Banthoon Sukphutanan, Wasuwit Wanchaitanawong and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

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  16. Journal of clinical medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 2 countries.

Pojsakorn DanpanichkulImmunology Unit, Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Kanokphong SuparanImmunology Unit, Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-6853-7387
Suchapa ArayakarnkulDepartment of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Aunchalee JaroenlapnopparatDepartment of Medicine, Mount Auburn Hospital, Beth Israel Lahey Health, Cambridge, MA 02138, USA.
Natchaya PolpichaiDepartment of Internal Medicine, Weiss Memorial Hospital, Chicago, IL 60640, USA.
Panisara FangsaardDepartment of Internal Medicine, Bassett Medical Center, Cooperstown, NY 13326, USA.
Siwanart KongarinFaculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Karan SrisurapanontFaculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Banthoon SukphutananFaculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Wasuwit WanchaitanawongDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Yatawee KanjanakotDepartment of Surgery, School of Medicine, Mae Fah Luang University, Chiang Rai 57100, Thailand.
Jakrapun PupaiboolDivision of Infectious Diseases, Department of Internal Medicine, University of Utah, Salt Lake City, UH 84112, USA.
Kwanjit DuangsonkDepartment of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Gursimran Singh KochharDivision of Gastroenterology and Hepatology, Allegheny Health Network, Pittsburgh, PA 15212, USA.
Karn WijarnpreechaDivision of Gastroenterology and Hepatology, Department of Medicine, University of Arizona College of Medicine, Phoenix, AZ 85004, USA.ORCID 0000-0002-6232-6343
Chiang Mai University · THAllegheny Health Network · USBassett Medical Center · USMae Fah Luang University · THMount Auburn Hospital · USUniversity of Arizona · USUniversity of Minnesota · USUniversity of Utah · USWeiss Memorial Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD), once thought to impact younger individuals, now manifests in approximately 10% of patients over 65, characterized by a heightened vulnerability to complications and greater diagnostic intricacies than conventional cases. However, comprehensive global epidemiological data regarding elderly-onset IBD are currently insufficient. Our study addresses this critical gap by analyzing trends in elderly-onset IBD over a decade, encompassing the estimation of annual frequencies and age-standardized rates of elderly-onset IBD burden for both genders, stratifying the data by geographical and sociodemographic factors. Our research highlights a notable increase in the proportion of elderly-onset IBD, constituting around 13% of all IBD cases. We observed a rising incidence in males, contrasted by a decreasing trend in females. The highest surge in incidence rates was seen in the Western Pacific region in both genders, but the highest burden was observed in America. Countries with high sociodemographic index (SDI) carried the greatest burden of elderly-onset IBD, while countries with low SDI had the least. The mortality and disability-adjusted life years (DALYs) rates trend downward in most regions. This study underscores an increasing incidence and proportion of IBD, particularly in elderly-onset IBD, particularly in males. While mortality and DALYs are decreasing in most regions, the overall burden remains highest in America and high-SDI countries. Effective public health interventions and comprehensive studies are required to tackle this mounting burden.

Indexed as

Crohn’s diseasegeriatricinflammatory bowel diseaseulcerative colitis

Identifiers

PMID37568544
PMCPMC10420121
OpenAlexW4385611737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.