ReviewJournal of clinical medicine2023
Frailty and Colorectal Surgery: Review and Concept of Cancer Frailty.
Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- One-Year Changes in Frailty Components After Curative Minimally Invasive Surgery for Colorectal Cancer in Older Patients.Annals of gastroenterological surgery · 2026Article
- Association of the Primary Care Frailty Index with Postoperative Outcomes in Older Patients Undergoing Major Gastrointestinal Oncologic Surgery: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Real-World Results of Curative Open Colorectal Cancer Surgery in Octogenarians: Long-Term Survival Despite High Frailty Burden.Medical sciences (Basel, Switzerland) · 2026Observational
- Frailty as a determinant of surgical morbidity, adjuvant therapy feasibility, and survival in octogenarian patients undergoing gastrointestinal cancer resection.BMC geriatrics · 2026Article
- Frailty, nutritional status, and inflammation as determinants of chemotherapy delivery and outcomes in pancreatic cancer patients receiving gemcitabine plus nab-paclitaxel.Frontiers in oncology · 2026Article
- Frailty Recovery Following Minimally Invasive Surgery: An Emerging Perspective on Surgical Benefits in Elderly Colorectal Cancer Patients.Annals of gastroenterological surgery · 2026Article
- Effects of digital health interventions on anxiety, depression, and quality of life in colorectal cancer patients: a meta-analysis of randomized controlled trials.Frontiers in oncology · 2026Review
- Development and validation of a Chinese version of the frailty risk perception questionnaire for older adults with colorectal cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Impacts of COVID-19 pandemic on short-term outcomes of low anterior resection performed in hospitals with different surgical volumes.Annals of gastroenterological surgery · 2025Article
- Risk factors for non-clinical prolonged lengths of stay after elective colorectal surgery.Scientific reports · 2025Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty is characterized by reduced physiological reserves across multiple systems. In patients with frailty, oncological surgery has been associated with a high rate of postoperative complications and worse overall survival. Further, given that cancer and frailty can co-exist in the same patient, cancer and cancer-related symptoms can rapidly accelerate the progression of baseline frailty, which we have termed "cancer frailty". This distinction is clinically meaningful because the prioritization of interventions and the treatment outcomes may differ based on health conditions. Specifically, in patients with cancer frailty, improvements in frailty may be achieved via surgical removal of tumors, while prehabilitation may be less effective, which may in turn result in delayed treatment and cancer progression. In this review, we focused on challenges in the surgical treatment of non-metastatic colorectal cancers in patients with frailty, including those related to decision making, prehabilitation, and surgery. Potential recommendations for treating patients with cancer frailty are also discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.