Evidence map›Paper›PMID 37568282›Full record

ArticleJournal of clinical medicine2023

A 21-Day Individual Rehabilitation Exercise Training Program Changes Irisin, Chemerin, and BDNF Levels in Patients after Hip or Knee Replacement Surgery.

Bronisława Skrzep-Poloczek, Maciej Idzik, Katarzyna Michalczyk, Elżbieta Chełmecka, Michał Kukla, Jolanta Zalejska-Fiolka, Jakub Poloczek, Bartosz Bogielski, Jerzy Jochem, Damian Nowak and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Bronisława Skrzep-PoloczekDepartment of Physiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Jordana 19 Street, 41-808 Zabrze, Poland.ORCID 0000-0002-3232-6377
Maciej IdzikIndependent Public Health Care, Opole Cancer Center Prof. Tadeusz Koszarowski, Katowicka 45-061 Street, 46-020 Opole, Poland.
Katarzyna MichalczykDepartment of Physiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Jordana 19 Street, 41-808 Zabrze, Poland.
Elżbieta ChełmeckaDepartment of Statistics, Department of Instrumental Analysis, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Ostrogórska 31 Street, 41-200 Sosnowiec, Poland.ORCID 0000-0002-0111-438X
Michał KuklaDepartment of Internal Medicine and Geriatrics, Jagiellonian University Medical College in Cracow, Jakubowskiego 28 Street, 31-501 Cracow, Poland.
Jolanta Zalejska-FiolkaDepartment of Biochemistry, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Jordana 19 Street, 41-808 Zabrze, Poland.ORCID 0000-0002-3879-6548
Jakub PoloczekDepartment of Rehabilitation, 3rd Specialist Hospital in Rybnik, Energetyków 46 Street, 44-200 Rybnik, Poland.
Bartosz BogielskiDepartment of Physiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Jordana 19 Street, 41-808 Zabrze, Poland.
Jerzy JochemDepartment of Physiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Jordana 19 Street, 41-808 Zabrze, Poland.
Damian NowakDepartment of Physiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Jordana 19 Street, 41-808 Zabrze, Poland.
Dominika StygarDepartment of Physiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Jordana 19 Street, 41-808 Zabrze, Poland.
Medical University of Silesia · PLJagiellonian University · PLPolska Grupa Energetyczna (Poland) · PLUniversity of Opole · PL

Funding

Medical University of Silesia in Katowice KNW/002/KB1/106/17
6 · The paper itself

Abstract

Osteoarthritis (OA) is the most frequent worldwide cause of adult population disabilities. The study evaluated the effects of a 21-day individual rehabilitation exercise training program focused on improving patients' functional capacity. The study analyzed the changes in irisin, chemerin, and BDNF serum levels in 36 OA patients subjected to an individually-adjusted rehabilitation program 90 days after surgical hip or knee replacement. The changes in irisin, chemerin, and BDNF serum levels were measured using enzyme-linked immunosorbent assay (ELISA) kits. A 21-day individual rehabilitation exercise training program significantly increased irisin and BDNF, and decreased chemerin serum levels. The presented study indicates that individually-adjusted exercise training is an important modulator influencing serum levels of anti- and pro-inflammatory factors, leading to positive clinical outcomes in osteoarthritis therapy. Selected factors are considered potential markers of various pathophysiological conditions. The presented study brings new details to the discussion.

Indexed as

brain-derived neurotrophic factor (BDNF)chemerinhip or knee replacement surgeryindividual rehabilitation exercise trainingirisinosteoarthritis

Identifiers

PMID37568282
PMCPMC10419925
OpenAlexW4385251991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.