Evidence map›Paper›PMID 37568193›Full record

ReviewCancer cell international2023

Recent advances in non-small cell lung cancer targeted therapy; an update review.

Mahmood Araghi, Reza Mannani, Ali Heidarnejad Maleki, Adel Hamidi, Samaneh Rostami, Salar Hozhabri Safa, Fatemeh Faramarzi, Sahar Khorasani, Mina Alimohammadi, Safa Tahmasebi and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancer cell international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 213 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
213citing papers in PubMed, 4 pooled it
70.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

213 citing papers in PubMed, 4 syntheses or guidelines pooled it, 272 citations in OpenAlex.

  1. Pooled it
  2. Diagnostic accuracy of next-generation sequencing (NGS) for identifying actionable mutations in advanced non-small cell lung cancer: Systematic Review and Meta-Analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Pooled it
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  10. Review
  11. Targeted therapeutic strategies forTranslational lung cancer research · 2026
    Review
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  13. Article
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  19. Incidence of new-onset atrial fibrillation after thoracic radiotherapy in non-small cell lung cancer: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  20. Article

153 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Mahmood AraghiDepartment of Pathology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Reza MannaniVascular Surgeon, Department of Surgery, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran. Dr_Reza_1349@yahoo.com.
Ali Heidarnejad MalekiSchool of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Adel HamidiRazi Vaccine and Serum Research Institute, Arak Branch, karaj, Iran.
Samaneh RostamiSchool of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Salar Hozhabri SafaSchool of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Fatemeh FaramarziDepartment of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Sahar KhorasaniDepartment of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Mina AlimohammadiDepartment of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-5953-3894
Safa TahmasebiStudent Research Committee, Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. safa.tahmasebi@sbmu.ac.ir.ORCID http://orcid.org/0000-0002-8598-1922
Reza Akhavan-SigariDepartment of Neurosurgery, University Medical Center, Tuebingen, Germany.
Zanjan University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRMazandaran University of Medical Sciences · IRRazi Vaccine and Serum Research Institute · IRTehran University of Medical Sciences · IRWarsaw Management University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer continues to be the leading cause of cancer-related death worldwide. In the last decade, significant advancements in the diagnosis and treatment of lung cancer, particularly NSCLC, have been achieved with the help of molecular translational research. Among the hopeful breakthroughs in therapeutic approaches, advances in targeted therapy have brought the most successful outcomes in NSCLC treatment. In targeted therapy, antagonists target the specific genes, proteins, or the microenvironment of tumors supporting cancer growth and survival. Indeed, cancer can be managed by blocking the target genes related to tumor cell progression without causing noticeable damage to normal cells. Currently, efforts have been focused on improving the targeted therapy aspects regarding the encouraging outcomes in cancer treatment and the quality of life of patients. Treatment with targeted therapy for NSCLC is changing rapidly due to the pace of scientific research. Accordingly, this updated study aimed to discuss the tumor target antigens comprehensively and targeted therapy-related agents in NSCLC. The current study also summarized the available clinical trial studies for NSCLC patients.

Indexed as

ImmunotherapyNSCLCTarget antigensTargeted therapy

Identifiers

PMID37568193
PMCPMC10416536
OpenAlexW4385763968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.