ArticleJournal of orthopaedic surgery and research2023
In primary total hip arthroplasty, the direct anterior approach leads to higher levels of creatine kinase and lower levels of C-reactive protein compared to the posterolateral approach: a propensity score matching analysis of short-term follow-up data.
Article in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Early clinical efficacy and safety of different surgical approaches in total hip arthroplasty: a systematic review and network meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Comparison of direct anterior vs. posterior approach in primary total hip arthroplasty: a systematic review and meta-analysis on enhanced recovery after surgery.Frontiers in surgery · 2025Pooled it
- Effect of a wound protector on soft-tissue injury and early recovery after endoscopic direct anterior approach total hip arthroplasty: a randomized controlled trial.Journal of orthopaedic surgery and research · 2026Trial
- Orthostatic intolerance following total joint arthroplasty remains a significant barrier to successful same-day discharge: a narrative review of an underreported complication.EFORT open reviews · 2026Review
- A novel iliofemoral classification for assessing surgical difficulty in direct anterior approach total hip arthroplasty: a retrospective cohort study.BMC musculoskeletal disorders · 2026Article
- Short Stem vs. Standard Stem in Primary Total Hip Replacement: A Perioperative Prospective Invasiveness Study with Serum Markers.Diseases (Basel, Switzerland) · 2025Article
- Comparison of autograft and allograft outcomes in adolescent ACL reconstruction: a propensity score analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Reduced polyethylene wear in dual mobility versus single mobility hip implants: Results from quantitative and qualitative scanning electron microscopy analysis.Journal of experimental orthopaedics · 2025Article
- Mid-term outcomes of medial metal backed and all-polyethylene unicompartmental knee arthroplasty in obese patients: a retrospective propensity-matched analysis.Journal of orthopaedic surgery and research · 2024Article
- Metal-backed or all-poly tibial components: which are better for medial unicompartmental knee arthroplasty? A propensity-score-matching retrospective study at the 5-year follow-up.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2024Article
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Authors and funding
7 authors.
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Abstract
backgroundThis retrospective study compares the invasiveness of the direct anterior approach (DAA) and the posterolateral approach (PLA) in total hip arthroplasty (THA) by assessing three widely used inflammation-related serum markers in the first ten post-operative days.
methodsThe database of our institution was mined for primary THAs conducted by the DAA or the PLA from February 2020 to June 2022. Demographics and creatine kinase (CK), C-reactive protein (CRP), and white blood cells were compared. Propensity Score Matching (PSM) analysis (1:1 ratio) was conducted based on multiple variables.
resultsPSM analysis yielded 44 pairs of DAA and PLA patients. CK was significantly higher (p < 0.001) in the DAA than in the PLA group on postoperative day (POD) 2, 5 and 10. The POD2, POD5 and POD10 CK/preoperative CK ratio was 12.9, 5.0 and 0.8 in DAA and 8.8, 3.3 and 0.6 in PLA (p = 0.017, p = 0.012 and p = 0.025, respectively). The POD2, POD5 and POD10 CRP/preoperative CRP ratio was 95.1, 65.6 and 22.8 in PLA and 34.7, 23.3 and 8.9 in DAA (p < 0.001, p = 0.002 and p < 0.001, respectively).
conclusionPSM analysis of early postoperative CK and CRP values demonstrated that the DAA should be considered as a less stressful approach, not as a muscle-sparing or a minimally invasive THA approach.
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