ArticleCommunications biology2023
microRNA165 and 166 modulate response of the Arabidopsis root apical meristem to salt stress.
Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 14 citations in OpenAlex.
- A Salt-ResponsiveInternational journal of molecular sciences · 2026Article
- Exploring differential gene correlations inBiotechnology reports (Amsterdam, Netherlands) · 2026Article
- Global analysis of soybean bZIP gene family under stress and identification of salt-stress-responsive candidate genes.Frontiers in plant science · 2026Article
- Genome-Wide Identification of theGenes · 2025Article
- The circadian clock of Populus affects physiological, transcriptional and metabolomic responses to osmotic and ionic components of salt stress.Npj biological timing and sleep · 2025Article
- Identification of a Specific Role of Dihydrozeatin in the Regulation of the Cell Differentiation Activity inPlants (Basel, Switzerland) · 2025Article
- Salt stress-accelerated proteasomal degradation of LBD11 suppresses ROS-mediated meristem development and root growth in Arabidopsis.Plant communications · 2025Article
- Dressed Up to the Nines: The Interplay of Phytohormones Signaling and Redox Metabolism During Plant Response to Drought.Plants (Basel, Switzerland) · 2025Review
- Article
- Unraveling Tissue-Specific miRNAs' Role in Plants Exploiting the GAL4/UAS System.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Salinity survival: molecular mechanisms and adaptive strategies in plants.Frontiers in plant science · 2025Review
- Identification and expression profiling of microRNAs in leaf tissues ofPlant signaling & behavior · 2024Article
- Insights into the Epigenetic Basis of Plant Salt Tolerance.International journal of molecular sciences · 2024Review
- Role of transcriptional regulation in auxin-mediated response to abiotic stresses.Frontiers in genetics · 2024Review
- Maintenance of stem cell activity in plant development and stress responses.Frontiers in plant science · 2023Review
Corrections and comments
- Erratum issued
Authors and funding
16 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plants, developmental plasticity allows for the modulation of organ growth in response to environmental cues. Being in contact with soil, roots are the first organ that responds to various types of soil abiotic stress such as high salt concentration. In the root, developmental plasticity relies on changes in the activity of the apical meristem, the region at the tip of the root where a set of self-renewing undifferentiated stem cells sustain growth. Here, we show that salt stress promotes differentiation of root meristem cells via reducing the dosage of the microRNAs miR165 and 166. By means of genetic, molecular and computational analysis, we show that the levels of miR165 and 166 respond to high salt concentration, and that miR165 and 166-dependent PHABULOSA (PHB) modulation is central to the response of root growth to this stress. Specifically, we show that salt-dependent reduction of miR165 and 166 causes a rapid increase in PHB expression and, hence, production of the root meristem pro-differentiation hormone cytokinin. Our data provide direct evidence for how the miRNA-dependent modulation of transcription factor dosage mediates plastic development in plants.
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