Evidence map›Paper›PMID 37567753›Full record

ArticleBMJ open2023

Pleural mesothelioma risk in the construction industry: a case-control study in Italy, 2000-2018.

Simona Stella, Dario Consonni, Enrica Migliore, Antonella Stura, Domenica Cavone, Luigi Vimercati, Lucia Miligi, Sara Piro, Maria Teresa Landi, Neil E Caporaso and 27 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors at 20 institutions in 2 countries.

Simona Stella *Occupational Health Unit, Regional Operating Center of Lombardy (COR Lombardia), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID 0000-0003-4276-2583
Dario Consonni *Occupational Health Unit, Regional Operating Center of Lombardy (COR Lombardia), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy dario.consonni@unimi.it.ORCID 0000-0002-8935-3843
Enrica MiglioreCOR Piemonte, Cancer Epidemiology Unit, CPO and University of Turin, Turin, Italy.ORCID 0000-0003-0121-6295
Antonella SturaCOR Piemonte, Cancer Epidemiology Unit, CPO and University of Turin, Turin, Italy.
Domenica CavoneCOR Puglia, Section of Occupational Medicine 'B Ramazzini', Department of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, Italy.ORCID 0000-0002-2009-1806
Luigi VimercatiCOR Puglia, Section of Occupational Medicine 'B Ramazzini', Department of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, Italy.ORCID 0000-0002-4072-2871
Lucia MiligiCOR Toscana, Unit of Environmental and Occupational Epidemiology, Institute for Cancer Research, Prevention and Clinical Network, Florence, Italy.ORCID 0000-0002-8223-485X
Sara PiroCOR Toscana, Unit of Environmental and Occupational Epidemiology, Institute for Cancer Research, Prevention and Clinical Network, Florence, Italy.ORCID 0000-0003-4198-7035
Maria Teresa LandiDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA.
Neil E CaporasoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA.ORCID 0000-0001-7562-4609
Stefania CurtiDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.ORCID 0000-0003-4343-8873
Stefano MattioliDepartment of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy.ORCID 0000-0002-9639-7430
Giovanni BrandiDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.ORCID 0000-0003-0013-2858
Carmela GiosciaCOR Valle d'Aosta, Valle d'Aosta Health Local Unit, Aosta, Italy.
Silvia EccherCOR Province of Trento, Provincial Unit of Health, Hygiene and Occupational Medicine, Trento, Italy.
Stefano MuranoCOR Province of Bolzano, Alto Adige Health Local Unit, Bolzano, Italy.
Veronica CasottoCOR Veneto, Epidemiological Department, Azienda Zero, Padova, Italy.
Vera ComiatiCOR Veneto, Epidemiological Department, Azienda Zero, Padova, Italy.
Corrado NegroCOR Friuli-Venezia Giulia, Clinical Unit of Occupational Medicine, University of Trieste-Trieste General Hospitals, Trieste, Italy.ORCID 0000-0002-2007-3608
Flavia D'AgostinCOR Friuli-Venezia Giulia, Clinical Unit of Occupational Medicine, University of Trieste-Trieste General Hospitals, Trieste, Italy.
Carlo GenovaUO Clinica di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genova, Italy.ORCID 0000-0003-3690-8582
Lucia BenfattoCOR Liguria, UO Epidemiologia Clinica, IRCCS Ospedale Policlinico San Martino, Genova, Liguria, Italy.
Antonio RomanelliCOR Emilia-Romagna, Public Health Department, Health Local Unit, Reggio Emilia, Italy.ORCID 0000-0003-4899-1889
Iolanda GrappasonniCOR Marche, School of Medicinal and Health Products Sciences, University of Camerino, Camerino, Italy.ORCID 0000-0003-1131-4286
Gabriella MadeoCOR Umbria, Servizio Prevenzione, Sanità Veterinaria e Sicurezza Alimentare, Regione Umbria, Perugia, Umbria, Italy.
Ilaria CozziCOR Lazio, Department of Epidemiology, Lazio Regional Health Service, ASL Roma 1, Rome, Lazio, Italy.ORCID 0000-0003-0313-9799
Elisa RomeoCOR Lazio, Department of Epidemiology, Lazio Regional Health Service, ASL Roma 1, Rome, Lazio, Italy.
Staniscia TommasoCOR Abruzzo, Abruzzo Regional Health Agency (ASR), Pescara, Italy.ORCID 0000-0002-5077-515X
Francesco CarrozzaCOR Molise, Registri Tumori Regione Molise, Campobasso, Italy.
Michele LabiancaCOR Basilicata, Epidemiologic Regional Center, Potenza, Italy.
Federico TallarigoCOR Calabria, Public Health Unit, Crotone, Italy.ORCID 0000-0002-4131-9531
Giuseppe CasconeCOR Sicilia, Cancer Registry ASP Ragusa and Sicily Regional Epidemiological Observatory, Ragusa, Italy.
Massimo MelisCOR Sardegna, Regional Epidemiological Center, Cagliari, Italy.
Alessandro MarinaccioOccupational and Environmental Medicine, Epidemiology and Hygiene Department, Italian Workers' Compensation Authority (INAIL), Rome, Italy.ORCID 0000-0001-9068-2137
Alessandra BinazziOccupational and Environmental Medicine, Epidemiology and Hygiene Department, Italian Workers' Compensation Authority (INAIL), Rome, Italy.ORCID 0000-0002-0435-600X
Carolina MensiOccupational Health Unit, Regional Operating Center of Lombardy (COR Lombardia), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID 0000-0002-9075-3684
ReNaM Working Group members
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITASL Roma · ITIstituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro · ITNational Cancer Institute · USOspedale Policlinico San Martino · ITPiedmont Reference Center for Epidemiology and Cancer Prevention · ITRegione del Veneto · ITUniversity of Bari Aldo Moro · ITUniversity of Trieste · ITAgenzia Sanitaria Regionale Abruzzo · ITAzienda USL di Bologna · ITCentro di Riferimento Oncologico della Basilicata · ITOspedale di Bolzano · ITProvincia Autonoma di Trento · ITRegione UmbriaUniversità di Camerino · ITUniversity of Aosta Valley · ITUniversity of Bologna · ITUniversity of Ferrara · ITUniversity of Molise · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWorkers in the construction industry have been exposed to asbestos in various occupations. In Italy, a National Mesothelioma Registry has been implemented more than 20 years ago. Using cases selected from this registry and exploiting existing control data sets, we estimated relative risks for pleural mesothelioma (PM) among construction workers.

designCase-control study.

settingCases from the National Mesothelioma Registry (2000-2018), controls from three previous case-control studies.

methodsWe selected male PM incident cases diagnosed in 2000-2018. Population controls were taken from three studies performed in six Italian regions within two periods (2002-2004 and 2012-2016). Age-adjusted and period-adjusted unconditional logistic regression models were fitted to estimate odds ratios (OR) for occupations in the construction industry. We followed two approaches, one (primary) excluding and the other (secondary) including subjects employed in other non-construction blue collar occupations for >5 years. For both approaches, we performed an overall analysis including all cases and, given the incomplete temporal and geographic overlap of cases and controls, three time or/and space restricted sensitivity analyses.

resultsThe whole data set included 15 592 cases and 2210 controls. With the primary approach (4797 cases and 1085 controls), OR was 3.64 (2181 cases) for subjects ever employed in construction. We found elevated risks for blue-collar occupations (1993 cases, OR 4.52), including bricklayers (988 cases, OR 7.05), general construction workers (320 cases, OR 4.66), plumbers and pipe fitters (305 cases, OR 9.13), painters (104 cases, OR 2.17) and several others. Sensitivity analyses yielded very similar findings. Using the secondary approach, we observed similar patterns, but ORs were remarkably lower.

conclusionsWe found markedly increased PM risks for most occupations in the construction industry. These findings are relevant for compensation of subjects affected with mesothelioma in the construction industry.

Indexed as

AsbestosConstruction IndustryMesotheliomaMesothelioma, MalignantOccupational DiseasesOccupational ExposurePleural NeoplasmsCase-Control StudiesHumansItalyLogistic ModelsMaleAsbestoscase-control studiesepidemiologyoccupational & industrial medicinepublic healthrespiratory tract tumours

Identifiers

PMID37567753
PMCPMC10423786
OpenAlexW4385778660

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.