Evidence map›Paper›PMID 37567150›Full record

ArticleBlood advances2023

Combining BCMA-targeting CAR T cells with TCR-engineered T-cell therapy to prevent immune escape of multiple myeloma.

Tassilo L A Wachsmann, Miranda H Meeuwsen, Dennis F G Remst, Karen Buchner, Anne K Wouters, Renate S Hagedoorn, J H Frederik Falkenburg, Mirjam H M Heemskerk

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Mapping the clinical landscape of multifunctional CAR T cells: Targets, trends, and synergies.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Secretory exosomes from modified immune cells against cancer.Medical oncology (Northwood, London, England) · 2025
    Review
  7. CAR-mediated target recognition limits TCR-mediated target recognition of TCR- and CAR-dual-receptor-edited T cells.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Are we there yet? CAR-T therapy in multiple myeloma.British journal of haematology · 2024
    Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tassilo L A WachsmannDepartment of Hematology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-9507-2530
Miranda H MeeuwsenDepartment of Hematology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-9268-3141
Dennis F G RemstDepartment of Hematology, Leiden University Medical Center, Leiden, The Netherlands.
Karen BuchnerDepartment of Hematology, Leiden University Medical Center, Leiden, The Netherlands.
Anne K WoutersDepartment of Hematology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-9861-7276
Renate S HagedoornDepartment of Hematology, Leiden University Medical Center, Leiden, The Netherlands.
J H Frederik FalkenburgDepartment of Hematology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-9819-4813
Mirjam H M HeemskerkDepartment of Hematology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-6320-9133
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Multiple MyelomaReceptors, Chimeric AntigenB-Cell Maturation AntigenCell- and Tissue-Based TherapyHumansT-LymphocytesB-Cell Maturation AntigenReceptors, Chimeric Antigen

Identifiers

PMID37567150
PMCPMC10582830
OpenAlexW4385755356

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.