Evidence map›Paper›PMID 37566649›Full record

ArticleScience advances2023

A secreted sirtuin from

Sean M Callahan, Trevor J Hancock, Ryan S Doster, Caroline B Parker, Mary E Wakim, Jennifer A Gaddy, Jeremiah G Johnson

Abstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Frontiers in veterinary science · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sean M CallahanDepartment of Microbiology, University of Tennessee, Knoxville, TN 37996, USA.ORCID 0000-0002-0581-6370
Trevor J HancockDepartment of Microbiology, University of Tennessee, Knoxville, TN 37996, USA.ORCID 0000-0002-3353-6042
Ryan S DosterDivision of Infectious Diseases, Department of Medicine Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0001-7376-1298
Caroline B ParkerDepartment of Microbiology, University of Tennessee, Knoxville, TN 37996, USA.
Mary E WakimDepartment of Microbiology, University of Tennessee, Knoxville, TN 37996, USA.
Jennifer A GaddyDivision of Infectious Diseases, Department of Medicine Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0002-2192-4224
Jeremiah G JohnsonDepartment of Microbiology, University of Tennessee, Knoxville, TN 37996, USA.ORCID 0000-0001-5302-3247

Funding

Determining the contribution of zinc deficiency to perinatal Group B Streptococcus infectionsR01HD090061 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ARONOFF, DAVID M, GADDY, JENNIFER A · 2017 to 2021
$2.5M
Integration of nutrient availability, TCA cycle activity, and colonization factor expression in Campylobacter jejuniR01AI166535 · NIAID · UNIVERSITY OF TENNESSEE KNOXVILLE · PI Jeremiah Johnson · 2022 to 2026
$1.9M
Defining the impact of zinc on Streptococcus agalactiae biofilm and colonizationK08AI151100 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DOSTER, RYAN S · 2020 to 2024
$927k
Toxicant Exposure Impacts Host-pathogen interactions within the Reproductive TractI01BX005352 · VA · VETERANS HEALTH ADMINISTRATION · PI GADDY, JENNIFER A · 2021 to 2024
–
BLRD VA I01 BX005352NIAID NIH HHS K08 AI151100NIAID NIH HHS R01 AI166535NICHD NIH HHS R01 HD090061
6 · The paper itself

Abstract

Histone modifications control numerous processes in eukaryotes, including inflammation. Some bacterial pathogens alter the activity or expression of host-derived factors, including sirtuins, to modify histones and induce responses that promote infection. In this study, we identified a deacetylase encoded by

Indexed as

Campylobacter InfectionsCampylobacter jejuniAnimalsHistonesHumansInflammationMiceNeutrophil ActivationHistones

Identifiers

PMID37566649
PMCPMC10421069

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.