Evidence map›Paper›PMID 37566643›Full record

ArticleThe Journal of urology2023

Comparing Patient-reported Functional Outcomes After Radical Prostatectomy in Historical and Contemporary Practice.

Udit Singhal, Brent K Hollenbeck, Samuel D Kaffenberger, Simpa S Salami, Arvin K George, Ted A Skolarus, Jeffrey S Montgomery, Daniela A Wittmann, David C Miller, John T Wei and 4 more

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Udit SinghalDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-3928-9476
Brent K HollenbeckDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-4840-1260
Samuel D KaffenbergerDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.
Simpa S SalamiDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0001-7461-7079
Arvin K GeorgeDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.
Ted A SkolarusDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-5859-8151
Jeffrey S MontgomeryDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.
Daniela A WittmannDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-9201-7269
David C MillerDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.
John T WeiDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.
Ganesh S PalapattuDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-9520-0480
James E MontieDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.
Rodney L DunnDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.
Todd M MorganDepartment of Urology, Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan.
University of Michigan · USJohns Hopkins University · USMayo Clinic · US

Funding

Tissue/InformaticsP50CA186786 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Robert Timothy Dess · 2014 to 2026
$27.6M
Determining the clinical impact of gene expression testing in localized prostate cancerR01CA240991 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MORGAN, TODD M., SPRATT, DANIEL EIDELBERG · 2019 to 2024
$3.1M
NCI NIH HHS L30 CA264387NCI NIH HHS P50 CA186786NCI NIH HHS R01 CA240991
6 · The paper itself

Abstract

purposeModifications to surgical technique, particularly the widespread adoption of robotic surgery, have been proposed to improve functional recovery after prostate cancer surgery. However, rigorous comparison of men in historical vs contemporary practice to evaluate the cumulative effect of these changes on urinary and sexual function after radical prostatectomy is lacking. MATERIALS AND

methodsWe compared prospectively collected patient-reported urinary and sexual function from historical (PROSTQA [Prostate Cancer Outcomes and Satisfaction With Treatment Quality Assessment study], n=235) and contemporary (MUSIC-PRO [Michigan Urological Surgery Improvement Collaborative Patient Reported Outcome] registry, n=1,215) cohorts at the University of Michigan to understand whether modern techniques have resulted in functional improvements for men undergoing prostate cancer surgery.

resultsWe found significant differences in baseline function, with better urinary (median [IQR]; 100 [93.8-100] vs 93.8 [85.5-100],

conclusionsOur results demonstrate that the widespread alterations in prostate cancer surgery over the past 2 decades have yielded improvements in sexual, but not urinary, function recovery.

Indexed as

Patient Reported Outcome MeasuresProstatectomyProstatic NeoplasmsRecovery of FunctionAgedErectile DysfunctionHumansMaleMiddle AgedProspective StudiesRegistriesRobotic Surgical ProceduresUrinary Incontinencepatient reported outcome measuresphysiologicalprostatectomyprostatic neoplasmssexual dysfunctionurinary incontinence

Identifiers

PMID37566643
PMCPMC11375504
OpenAlexW4385754901

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.