Evidence map›Paper›PMID 37566345›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2023

Expert consensus to optimize the management of older adult patients with advanced EGFR-mutated non-small cell lung cancer.

Ernest Nadal, Martín Oré-Arce, Jordi Remon, Reyes Bernabé-Caro, Marta Covela-Rúa, Javier de Castro-Carpeño, Bartomeu Massutí-Sureda, Mónica Guillot-Morales, Margarita Majem, Inmaculada Maestu-Maiques and 2 more

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 12 institutions in 1 country.

Ernest NadalDepartment of Medical Oncology, Institut Català d'Oncologia (ICO), Institut d'Investigacions Biomèdiques de Bellvitge (IDIBELL), Duran i Reynals University Hospital, Barcelona, Spain.
Martín Oré-ArceDepartment of Medical Oncology, Marina Baixa de Villajoyosa Hospital, Alicante, Spain.
Jordi RemonDepartment of Medical Oncology, HM Nou Delfos Hospital, Barcelona, Spain.
Reyes Bernabé-CaroDepartment of Medical Oncology, Virgen del Rocío University Hospital, Sevilla University, Seville, Spain.
Marta Covela-RúaDepartment of Medical Oncology, Lucus Augusti University Hospital, Lugo, Spain.
Javier de Castro-CarpeñoDepartment of Medical Oncology, La Paz University Hospital, IdiPAZ, Madrid, Spain.
Bartomeu Massutí-SuredaDepartment of Medical Oncology, Alicante General University Hospital, Alicante, Spain.
Mónica Guillot-MoralesDepartment of Medical Oncology, Son Espases University Hospital, Palma, Spain.
Margarita MajemDepartment of Medical Oncology, Santa Creu i Sant Pau Hospital, Barcelona, Spain.
Inmaculada Maestu-MaiquesDepartment of Medical Oncology, Dr. Peset University Hospital, Valencia, Spain.
Idoia Morilla-RuízDepartment of Medical Oncology, Navarra University Hospital-NavarraBioMed, IdisNa, Pamplona, Spain.
Regina GironésDepartment of Medical Oncology, Polytechnic la Fe University Hospital, Avinguda de Fernando Abril Martorell, 106, 46026, Valencia, Valencia, Spain. reginagiro@hotmail.com.ORCID http://orcid.org/0000-0002-5548-0553
Delfos Hospital · ESHospital de Sant Pau · ESHospital General Universitario de Alicante Doctor Balmis · ESHospital Marina Baixa · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario Doctor Peset · ESHospital Universitario La Paz · ESHospital Universitario Lucus Augusti · ESHospital Universitario Son Espases · ESHospital Universitario Virgen del Rocío · ESInstitut d'Investigació Biomédica de Bellvitge · ESNavarre Institute of Health Research · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer (LC) is associated with ageing, with the average age of affected individuals being approximately 70 years. However, despite a higher incidence and prevalence among older people, the older adult population is underrepresented in clinical trials. For LC with Epidermal Growth Factor Receptor (EGFR) mutations, there is no clear association of this mutation with age. Geriatric assessments (GAs) and a multidisciplinary approach are essential for defining the optimal treatment. In this consensus, a group of experts selected from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (Sección de Oncogeriatría de la Sociedad Española de Oncología Médica-SEOM), the Spanish Lung Cancer Group (Grupo Español de Cáncer de Pulmón-GECP) and the Association for Research on Lung Cancer in Women (Asociación para la Investigación del Cáncer de Pulmón en Mujeres-ICAPEM) evaluate the scientific evidence currently available and propose a series of recommendations to optimize the management of older adult patients with advanced LC with EGFR mutations.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsAgedConsensusErbB ReceptorsFemaleHumansMedical OncologyEGFR protein, humanErbB ReceptorsEGFR mutationGeriatric assessmentLung cancerOlder adult patientTargeted therapyTKI

Identifiers

PMID37566345
PMCPMC10514135
OpenAlexW4385751283

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.