Evidence map›Paper›PMID 37566317›Full record

ArticleJournal of assisted reproduction and genetics2023

Clinical pregnancy in Turner syndrome following re-implantation of cryopreserved ovarian cortex.

C E Dunlop, S A Jack, E E Telfer, S Zahra, R A Anderson

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Clinical practice guidelines for the management of differences of sex development in Japan.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2026
    Review
  9. Review
  10. Approach to the Patient With Turner Syndrome.The Journal of clinical endocrinology and metabolism · 2025
    Review
  11. Article
  12. Medically assisted reproduction comes to the rescue….again and again!Journal of assisted reproduction and genetics · 2025
    Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

C E DunlopSimpson's Centre for Reproductive Health, Edinburgh Royal Infirmary, Edinburgh, EH16 4SA, UK. Cheryl.Dunlop@nhslothian.scot.nhs.uk.ORCID http://orcid.org/0009-0004-0104-2349
S A JackSimpson's Centre for Reproductive Health, Edinburgh Royal Infirmary, Edinburgh, EH16 4SA, UK.
E E TelferInstitute of Cell Biology and CDBS, University of Edinburgh, Edinburgh, EH8 9XD, UK.
S ZahraTissues, Cells & Advanced Therapeutics, Scottish National Blood Transfusion Service, Edinburgh, EH14 4BE, UK.
R A AndersonSimpson's Centre for Reproductive Health, Edinburgh Royal Infirmary, Edinburgh, EH16 4SA, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Turner syndrome (TS) leads to a characteristic phenotype, including premature ovarian insufficiency and infertility. Ovarian tissue cryopreservation (OTC) is becoming an established fertility preservation strategy for both pre- and post-pubertal females and may offer the chance of having a biological family to selected patients with TS. To date, women with TS have had ovarian tissue cryopreserved but there are few reports of autologous re-implantation and none of pregnancy. We herein report, to our knowledge, the first clinical pregnancy in a patient with TS, conceived naturally following re-implantation of cryopreserved ovarian tissue which had been removed soon after spontaneous puberty. This provides proof of concept for OTC as a means of fertility preservation in TS.

Indexed as

Fertility PreservationPrimary Ovarian InsufficiencyTurner SyndromeCryopreservationFemaleHumansPregnancyFertility preservationOvarian cortex re-implantationPremature ovarian insufficiencyTurner syndrome

Identifiers

PMID37566317
PMCPMC10504145

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.