Evidence map›Paper›PMID 37566251›Full record

ArticleBulletin of experimental biology and medicine2023

Blood Cytokines of the Ovarian Vein Basin in Different Stages of Pelvic Varicose Veins.

M A Darenskaya, A A Semendyaev, D A Stupin, S I Kolesnikov, N V Semenova, K V Pesterev, L I Kolesnikova

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

M A DarenskayaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia. marina_darenskaya@inbox.ru.
A A SemendyaevIrkutsk State Medical University, Ministry of health of the Russian Federation, Irkutsk, Russia.
D A StupinScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
S I KolesnikovScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
N V SemenovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
K V PesterevIrkutsk State Medical University, Ministry of health of the Russian Federation, Irkutsk, Russia.
L I KolesnikovaScientific Center for Family Health and Human Reproduction Problems, Irkutsk, Russia.
Irkutsk State Medical University · RUScientific Center of Family Health Problems and Human Reproduction · RUIrkutsk State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We analyzed the blood concentration of pro- and anti-inflammatory cytokines in the ovarian vein basin area in women of the reproductive age with primary pelvic varices. Increase in the disease severity was accompanied by a significant increase in proinflammatory cytokines (TNFα, IL-1β, IL-2, IL-6, and IL-8) and the proinflammatory index (IL-6/IL-10), whereas anti-inflammatory cytokine production changed ambiguously (increase of IL-4 at stage I, decrease of IL-10 at stage II, significant decrease of IL-4 and IL-10 at stage III). Control of these changes in female patients should probably be an important component of treatment measures and prevention of morphofunctional disorders occurring at disease progression, in particular at stage III of the disease.

Indexed as

CytokinesVaricose VeinsAnti-Inflammatory AgentsFemaleHumansInterleukin-10Interleukin-4Interleukin-6Anti-Inflammatory AgentsCytokinesInterleukin-10Interleukin-4Interleukin-6cytokinespelvic varicose veinswomen

Identifiers

PMID37566251
OpenAlexW4385751587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.