Evidence map›Paper›PMID 37566063›Full record

ArticleCells2023

The Impact of CC16 on Pulmonary Epithelial-Driven Host Responses during

Natalie Iannuzo, Alane Blythe C Dy, Stefano Guerra, Paul R Langlais, Julie G Ledford

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Natalie IannuzoDepartment of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724, USA.
Alane Blythe C DyAsthma and Airway Disease Research Center, Tucson, AZ 85724, USA.ORCID 0000-0002-9899-6090
Stefano GuerraAsthma and Airway Disease Research Center, Tucson, AZ 85724, USA.
Paul R LanglaisDepartment of Medicine, Division of Endocrinology, University of Arizona, Tucson, AZ 85724, USA.ORCID 0000-0003-1929-737X
Julie G LedfordDepartment of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724, USA.ORCID 0000-0001-7977-4575
University of Arizona · USDermatology Research Center · US

Funding

PHYSIOLOGYT32HL007249 · NHLBI · UNIVERSITY OF ARIZONA · PI Brett A Colson, JOHN P KONHILAS · 1985 to 2026
$12.5M
CC16 in Childhood and Resilience to Persistent Asthma into Adult Life (Supplement)R01AI135108 · NIAID · UNIVERSITY OF ARIZONA · PI Stefano Guerra · 2017 to 2026
$5.4M
Defining mechanisms of CC16 on epithelial-driven host responses to pathogensR01HL142769 · NHLBI · UNIVERSITY OF ARIZONA · PI Julie Gunnells Ledford · 2019 to 2026
$4.2M
NHLBI NIH HHS R01 HL142769NHLBI NIH HHS T32 HL007249NIAID NIH HHS R01 AI135108
6 · The paper itself

Abstract

Club Cell Secretory Protein (CC16) plays many protective roles within the lung; however, the complete biological functions, especially regarding the pulmonary epithelium during infection, remain undefined. We have previously shown that CC16-deficient (CC16

Indexed as

Pneumonia, MycoplasmaUteroglobinAnimalsEpithelial CellsEpitheliumLungMiceMice, KnockoutProteinsProteinsScgb1a1 protein, mouseUteroglobinairway epitheliumCC16mass spectrometryMycoplasma pneumoniaequantitative proteomics

Identifiers

PMID37566063
PMCPMC10416898
OpenAlexW4385461556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.