Evidence map›Paper›PMID 37565768›Full record

ArticleACS infectious diseases2023

An Oral Microbial Biomarker for Early Detection of Recurrence of Oral Squamous Cell Carcinoma.

Wei-Ni Lyu, Mei-Chun Lin, Cheng-Ying Shen, Li-Han Chen, Yung-Hua Lee, Shin-Kuang Chen, Liang-Chuan Lai, Eric Y Chuang, Pei-Jen Lou, Mong-Hsun Tsai

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Wei-Ni LyuInstitute of Biotechnology, National Taiwan University, Taipei 10617, Taiwan.
Mei-Chun LinDepartment of Otolaryngology, National Taiwan University Hospital, Taipei 10002, Taiwan.
Cheng-Ying ShenInstitute of Biotechnology, National Taiwan University, Taipei 10617, Taiwan.
Li-Han ChenInstitute of Fisheries Science, National Taiwan University, Taipei 10617, Taiwan.
Yung-Hua LeeInstitute of Biotechnology, National Taiwan University, Taipei 10617, Taiwan.
Shin-Kuang ChenCenter for Biotechnology, National Taiwan University, Taipei 10617, Taiwan.
Liang-Chuan LaiGraduate Institute of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.ORCID 0000-0002-3913-5338
Eric Y ChuangGraduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei 10617, Taiwan.
Pei-Jen LouDepartment of Otolaryngology, National Taiwan University Hospital, Taipei 10002, Taiwan.
Mong-Hsun TsaiInstitute of Biotechnology, National Taiwan University, Taipei 10617, Taiwan.ORCID 0000-0001-5905-1193
National Taiwan University · TWNational Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Changes in the oral microbiome are associated with oral squamous cell carcinoma (OSCC). Oral microbe-derived signatures have been utilized as markers of OSCC. However, the structure of the oral microbiome during OSCC recurrence and biomarkers for the prediction of OSCC recurrence remains unknown. To identify OSCC recurrence-associated microbial biomarkers for the prediction of OSCC recurrence, we performed 16S rRNA amplicon sequencing on 54 oral swab samples from OSCC patients. Differences in bacterial compositions were observed in patients with vs without recurrence. We found that

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsMouth NeoplasmsBiomarkersHumansRNA, Ribosomal, 16SSquamous Cell Carcinoma of Head and NeckBiomarkersRNA, Ribosomal, 16Smicrobial biomarkersmicrobiomeoral squamous cell carcinomarecurrence

Identifiers

PMID37565768
PMCPMC10496842
OpenAlexW4385751254

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.