Evidence map›Paper›PMID 37565749›Full record

ArticleJournal of virology2023

Stabilization of the human cytomegalovirus UL136p33 reactivation determinant overcomes the requirement for UL135 for replication in hematopoietic cells.

Melissa A Moy, Donna Collins-McMillen, Lindsey Crawford, Christopher Parkins, Sebastian Zeltzer, Katie Caviness, Syed Shujaat Ali Zaidi, Patrizia Caposio, Felicia Goodrum

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Viral and host network analysis of the human cytomegalovirus transcriptome in latency.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Human cytomegalovirus and neonatal infection.Current research in microbial sciences · 2024
    Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Melissa A MoyCancer Biology Graduate Interdisciplinary Program, University of Arizona , Tucson, Arizona, USA.
Donna Collins-McMillenDepartment of Immunobiology, University of Arizona , Tucson, Arizona, USA.
Lindsey CrawfordVaccine and Gene Therapy Institute, Oregon Health and Science University , Beaverton, Oregon, USA.
Christopher ParkinsVaccine and Gene Therapy Institute, Oregon Health and Science University , Beaverton, Oregon, USA.
Sebastian ZeltzerDepartment of Immunobiology, University of Arizona , Tucson, Arizona, USA.
Katie CavinessDepartment of Immunobiology, University of Arizona , Tucson, Arizona, USA.
Syed Shujaat Ali ZaidiDepartment of Immunobiology, University of Arizona , Tucson, Arizona, USA.
Patrizia CaposioVaccine and Gene Therapy Institute, Oregon Health and Science University , Beaverton, Oregon, USA.ORCID 0000-0001-7579-849X
Felicia GoodrumCancer Biology Graduate Interdisciplinary Program, University of Arizona , Tucson, Arizona, USA.ORCID 0000-0002-6646-7290
University of Arizona · USOregon Health & Science University · US

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
The Administrative CoreP01AI127335 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI Patrizia Caposio · 2017 to 2026
$24.6M
Mechanisms of Human Cytomegalovirus Latency in Primary Human Hematopoietic CellsR01AI079059 · NIAID · UNIVERSITY OF ARIZONA · PI GOODRUM, FELICIA D · 2008 to 2018
$4.4M
Mechanisms of Human Cytomegalovirus Latency in Primary Human Hematopoietic CellsR37AI079059 · NIAID · UNIVERSITY OF ARIZONA · PI Felicia D Goodrum · 2019 to 2026
$3.3M
NCI NIH HHS P30 CA023074NIAID NIH HHS P01 AI127335NIAID NIH HHS R01 AI079059NIAID NIH HHS R37 AI079059
6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) is a beta herpesvirus that persists indefinitely in the human host through a latent infection. The polycistronic

Indexed as

CytomegalovirusLatent InfectionAnimalsAntigens, CD34HumansMiceMice, Inbred NODViral ProteinsVirus LatencyVirus ReplicationAntigens, CD34UL136 protein, human herpesvirus 5Viral ProteinscytomegalovirusherpesviruslatencyreactivationUL135UL136

Identifiers

PMID37565749
PMCPMC10506481
OpenAlexW4385752148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.