ArticleCureus2023
Investigating the Link Between Abdominal Pain, Weight Loss, and IgG4-Related Pancreatitis: A Case Report.
Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This case report describes a 55-year-old male who presented with a two-year history of abdominal pain and weight loss, along with recent onset nausea, vomiting, and anorexia. Laboratory tests revealed elevated serum IgG4 levels and anemia, and abdominal CT showed diffuse pancreatic enlargement and multiple retroperitoneal lymphadenopathy. Endoscopic ultrasound-guided fine-needle aspiration of the pancreatic mass revealed dense lymphoplasmacytic infiltration with fibrosis and increased numbers of IgG4-positive plasma cells, consistent with the diagnosis of IgG4-related pancreatitis. Treatment with prednisone led to a significant improvement in the patient's symptoms and laboratory values, with subsequent reduction in the size of the pancreatic mass and retroperitoneal lymphadenopathy. The patient remained asymptomatic at the six-month follow-up visit, and serum IgG4 levels remained within the normal range. This case highlights the importance of considering IgG4-related disease (IgG4-RD) in patients presenting with abdominal pain and weight loss and the potential effectiveness of corticosteroid therapy in managing this condition.
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