Evidence map›Paper›PMID 37564785›Full record

ReviewFrontiers in molecular neuroscience2023

Epigenetic embedding of childhood adversity: mitochondrial metabolism and neurobiology of stress-related CNS diseases.

Benedetta Bigio, Yotam Sagi, Olivia Barnhill, Josh Dobbin, Omar El Shahawy, Paolo de Angelis, Carla Nasca

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Adverse childhood experiences influence markers of neurodegeneration risk in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Benedetta BigioDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY, United States.
Yotam SagiDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY, United States.
Olivia BarnhillHarold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, Rockefeller University, New York, NY, United States.
Josh DobbinHarold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, Rockefeller University, New York, NY, United States.
Omar El ShahawyDepartment of Population Health, New York University Grossman School of Medicine, New York, NY, United States.
Paolo de AngelisHarold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, Rockefeller University, New York, NY, United States.
Carla NascaDepartment of Psychiatry, New York University Grossman School of Medicine, New York, NY, United States.
New York University · USRockefeller University · USNathan Kline Institute for Psychiatric Research · US

Funding

A translational approach for novel mechanisms of epigenetic regulation in treatment responses: toward a precision medicine modelR01MH128311 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Carla Nasca · 2022 to 2026
$3.6M
Novel mechanisms of epigenetic regulation in stress and depression: toward a precision medicine modelR56MH125895 · NIMH · ROCKEFELLER UNIVERSITY · PI NASCA, CARLA · 2021 to 2022
$834k
Reversibility Network: Interventions to Reverse or Remediate Effects of Early Life Adversity on Ageing ProcessesR24AG065174 · NIA · BROWN UNIVERSITY · PI GODFREY, KEITH, LOUCKS, ERIC · 2020 to 2020
$421k
NIMH NIH HHS R01 MH128311NIMH NIH HHS R56 MH125895
6 · The paper itself

Abstract

This invited article ad memoriam of Bruce McEwen discusses emerging epigenetic mechanisms underlying the

Indexed as

acetyl-L-carnitinecognitiondepressionglutamatehippocampushistonemood disordersopioid use disorders

Identifiers

PMID37564785
PMCPMC10411541
OpenAlexW4385240124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.