Evidence map›Paper›PMID 37563553›Full record

ArticleBMC geriatrics2023

Interrupting bedtime to reverse frailty levels in acute care: a study protocol for the Breaking Bad Rest randomized controlled trial.

Olga Theou, Myles W O'Brien, Judith Godin, Chris Blanchard, Leah Cahill, Mohammad Hajizadeh, Peter Hartley, Pamala Jarrett, Dustin Scott Kehler, Roman Romero-Ortuno and 2 more

2 registry-linked trialsOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03682523 nacompletednot on this map

The Breaking "Bad Rest" Study: Interrupting Sedentary Time to Reverse Frailty Levels in Acute Care

TypeinterventionalSponsorOlga TheouRan2022 to 2023Enrolled50ConditionsSedentary LifestyleArmsSedentary behavior reduction intervention
NCT06810661 narecruitingnot on this mapstarted 2025, after this paper: background citation

Managing Frailty Through Mobilization in Males and Female Inpatients With Cardiovascular Disease

TypeinterventionalSponsorUniversité de SherbrookeRan2025 to 2026Enrolled60ConditionsCardiovascular Diseases, FrailtyArmsMobility promotion
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Olga TheouSchool of Physiotherapy, Dalhousie University, Halifax, NS, Canada. olga.theou@dal.ca.
Myles W O'BrienSchool of Physiotherapy, Dalhousie University, Halifax, NS, Canada.
Judith GodinDivision of Geriatric Medicine, Dalhousie University and Nova Scotia Health, Halifax, NS, Canada.
Chris BlanchardDepartment of Medicine, Dalhousie University, Halifax, NS, Canada.
Leah CahillDepartment of Medicine, Dalhousie University, Halifax, NS, Canada.
Mohammad HajizadehSchool of Health Administration, Faculty of Health, Dalhousie University, Halifax, NS, Canada.
Peter HartleyDepartment of Physiotherapy, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK.
Pamala JarrettGeriatric Medicine, Horizon Health Network, Dalhousie University, Saint John, New Brunswick, Canada.
Dustin Scott KehlerSchool of Physiotherapy, Dalhousie University, Halifax, NS, Canada.
Roman Romero-OrtunoDiscipline of Medical Gerontology, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Renuka VisvanathanAdelaide Geriatrics Training and Research with Aged Care (GTRAC) Centre, School of Medicine, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, South Australia, Australia.
Kenneth RockwoodDivision of Geriatric Medicine, Dalhousie University and Nova Scotia Health, Halifax, NS, Canada.
Dalhousie University · CANova Scotia Health Authority · CABasil Hetzel Institute · AUCambridge University Hospitals NHS Foundation Trust · GBTrinity College Dublin · IE

Funding

CIHR MFE-181747
6 · The paper itself

Abstract

backgroundHospitalized older patients spend most of the waking hours in bed, even if they can walk independently. Excessive bedrest contributes to the development of frailty and worse hospital outcomes. We describe the study protocol for the Breaking Bad Rest Study, a randomized clinical trial aimed to promoting more movement in acute care using a novel device-based approach that could mitigate the impact of too much bedrest on frailty.

methodsFifty patients in a geriatric unit will be randomized into an intervention or usual care control group. Both groups will be equipped with an activPAL (a measure of posture) and StepWatch (a measure of step counts) to wear throughout their entire hospital stay to capture their physical activity levels and posture. Frailty will be assessed via a multi-item questionnaire assessing health deficits at admission, weekly for the first month, then monthly thereafter, and at 1-month post-discharge. Secondary measures including geriatric assessments, cognitive function, falls, and hospital re-admissions will be assessed. Mixed models for repeated measures will determine whether daily activity differed between groups, changed over the course of their hospital stay, and impacted frailty levels. DISCUSSION: This randomized clinical trial will add to the evidence base on addressing frailty in older adults in acute care settings through a devices-based movement intervention. The findings of this trial may inform guidelines for limiting time spent sedentary or in bed during a patient's stay in geriatric units, with the intention of scaling up this study model to other acute care sites if successful.

trial registrationThe protocol has been registered at clinicaltrials.gov (identifier: NCT03682523).

Indexed as

FrailtyAftercareAgedExercise TherapyHumansPatient DischargeQuality of LifeRandomized Controlled Trials as TopicTreatment OutcomeActivPALFrailtyGeriatric medicineSedentary timeStep countsStepWatch

Identifiers

PMID37563553
PMCPMC10416381
OpenAlexW4385719795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.