Evidence map›Paper›PMID 37563534›Full record

ArticleBulletin of experimental biology and medicine2023

Antimicrobial Activity of Milk Whey in Different Mammals.

T I Kolyganova, V G Arzumanyan, M A Matvienko, A A Rodionova, D S Korshunova, P O Shatunova, N E Yastrebova

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

T I KolyganovaDepartment of Microbiology, Virology, and Immunology, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia. tatianakolyganova@mail.ru.
V G ArzumanyanI. I. Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia.
M A MatvienkoAll-Russian Research Institute of Horse Breeding, Divovo, Rybnovsky district, Ryazan region, Russia.
A A RodionovaAll-Russian Research Institute of Horse Breeding, Divovo, Rybnovsky district, Ryazan region, Russia.
D S KorshunovaInstitute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
P O ShatunovaDepartment of Microbiology, Virology, and Immunology, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia.
N E YastrebovaI. I. Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia.
Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences · RUAll-Russian Scientific - Research Institute of Horse Breeding · RUInstitute of Gene Biology · RUSechenov University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial activity of milk whey in different mammals against Candida albicans yeast cells was studied by a spectrophotometric method. The activity increased in the order goat→horse→camel→cow→human→mouse. The level of whey activity in mice was higher by 3 and 10 times than in humans and goats, respectively. Similar changes were noted for activity of the whey fraction <100 kDa containing a complex of antimicrobial polypeptides, and there was a direct correlation between these two parameters (r=0.881; p<0.05). The total activity of whey had a high degree of correlation with the content of serum albumin (r=0.992); in mice, the level of serum albumin in the milk whey was close to that in blood serum. Interspecific differences between the activity of whey in mammals may be associated with qualitative and quantitative variability of the antimicrobial polypeptide composition, as well as their synergistic or antagonistic interaction with each other.

Indexed as

MilkWheyAnimalsCattleFemaleGoatsHorsesHumansMammalsMicePeptidesWhey ProteinsPeptidesWhey Proteinsantimicrobial activityantimicrobial peptidesbreast milkCandida albicansmammals

Identifiers

PMID37563534
OpenAlexW4385719185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.