Evidence map›Paper›PMID 37563454›Full record

ReviewNature reviews. Cardiology2024

Valvular heart disease and cardiomyopathy: reappraisal of their interplay.

Nina Ajmone Marsan, Francesca Graziani, Maria Chiara Meucci, Hoi W Wu, Rosa Lillo, Jeroen J Bax, Francesco Burzotta, Massimo Massetti, J Wouter Jukema, Filippo Crea

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Clinical application of cardiac computed tomography in cardiomyopathy.The international journal of cardiovascular imaging · 2026
    Review
  2. Article
  3. Article
  4. Multifaceted roles of neutrophils in cardiac disease.Journal of leukocyte biology · 2025
    Review
  5. Right atrial strain in Anderson-Fabry disease.Frontiers in cardiovascular medicine · 2025
    Article
  6. Article
  7. Article
  8. Role of standard echocardiography in Anderson-Fabry disease.Frontiers in cardiovascular medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nina Ajmone Marsan *Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands. n.ajmone@lumc.nl.ORCID 0000-0001-7208-5769
Francesca Graziani *Department of Cardiovascular Science, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Maria Chiara MeucciDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-5474-0555
Hoi W WuDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Rosa LilloDepartment of Cardiovascular Science, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Jeroen J BaxDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Francesco BurzottaDepartment of Cardiovascular Science, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Massimo MassettiDepartment of Cardiovascular Science, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
J Wouter JukemaDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-3246-8359
Filippo CreaDepartment of Cardiovascular Science, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiomyopathies and valvular heart diseases are typically considered distinct diagnostic categories with dedicated guidelines for their management. However, the interplay between these conditions is increasingly being recognized and they frequently coexist, as in the paradigmatic examples of dilated cardiomyopathy and hypertrophic cardiomyopathy, which are often complicated by the occurrence of mitral regurgitation. Moreover, cardiomyopathies and valvular heart diseases can have a shared aetiology because several genetic or acquired diseases can affect both the cardiac valves and the myocardium. In addition, the association between cardiomyopathies and valvular heart diseases has important prognostic and therapeutic implications. Therefore, a better understanding of their shared pathophysiological mechanisms, as well as of the prevalence and predisposing factors to their association, might lead to a different approach in the risk stratification and management of these diseases. In this Review, we discuss the different scenarios in which valvular heart diseases and cardiomyopathies coexist, highlighting the need for an improved classification and clustering of these diseases with potential repercussions in the clinical management and, particularly, personalized therapeutic approaches.

Indexed as

CardiomyopathiesCardiomyopathy, DilatedCardiomyopathy, HypertrophicHeart Valve DiseasesHumansMyocardium

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.