ArticleScientific reports2023
Analysis of risk factors for postoperative delirium in middle-aged and elderly fracture patients in the perioperative period.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Study on the predictive model of delirium risk after surgery for elderly hip fractures based on meta-analysis.European geriatric medicine · 2025Pooled it
- Clinical and Inflammatory Determinants of Postoperative Delirium After Hip Fracture Surgery: A Retrospective Cohort Study of 962 Patients.Medicina (Kaunas, Lithuania) · 2026Article
- Perioperative interventions in preventing postoperative delirium following orthopaedic surgery in the elderly: a Bayesian network meta-analysis.Journal of orthopaedic translation · 2026Review
- Intravenous Tranexamic Acid Reduces the Incidence of Postoperative Delirium in Elderly Patients Undergoing Hip Arthroplasty: A Retrospective Cohort Study.Drug design, development and therapy · 2026Article
- Association between tranexamic acid and postoperative delirium in elderly patients: a mediation analysis of inflammatory markers following hip and knee arthroplasty.Frontiers in medicine · 2026Article
- Recent advances in postoperative delirium in elderly patients: pathophysiological mechanisms, risk prediction, and therapeutic strategies.Frontiers in neuroscience · 2026Review
- Preoperative hypocalcemia predicts postoperative complications in older orthopedic patients: A multicenter cohort study.PloS one · 2026Article
- Establishment of a postoperative delirium risk prediction model for elderly hip fracture patients based on machine learning algorithms.BMC geriatrics · 2025Article
- Risk Factors for Emergence Delirium in Elderly Orthopedic Patients After General Anesthesia.Brain and behavior · 2025Observational
- Post-operative Delirium in Orthopedic Fracture Patients: Challenges and Strategies.Journal of orthopaedic case reports · 2025Article
- High prevalence of unrecognized postoperative delirium in elderly patients: a prospective cohort study from a resource-limited country.Patient safety in surgery · 2025Article
- Glycated Hemoglobin as a Predictor of Postoperative Delirium in Diabetic Patients Undergoing Noncardiac Surgery: A Retrospective Study.Medicina (Kaunas, Lithuania) · 2025Article
- Effect of preoperative rapamycin supplementation on perioperative clinical frailty and cognitive performance in a murine model undergoing anesthesia and surgery.Scientific reports · 2025Article
- [Risk of postoperative delirium in older adults under balanced general anesthesia].Revista medica del Instituto Mexicano del Seguro Social · 2024Article
- Former smoking, but not active smoking, is associated with delirium in postoperative ICU patients: a matched case-control study.Frontiers in psychiatry · 2024Article
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Authors and funding
7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
To investigate the incidence rate and risk factors of postoperative delirium in middle-aged and elderly patients with fracture. A total of 648 middle-aged and elderly fracture patients who underwent surgical treatment in our hospital from January 2018 to December 2020 were included in the study, aged 50-103 years, mean 70.10 ± 11.37 years. The incidence of postoperative delirium was analyzed. Univariate analysis was used to screen the risk factors of gender, age, interval between injury and operation, preoperative complications, fracture site, anesthesia method, operation time, intraoperative blood loss, hidden blood loss and hormone use. For the factors with P < 0.05, multivariate logistic regression analysis was used to determine the main independent risk factors. 115 cases (17.74%) of 648 patients had postoperative delirium. Univariate analysis showed that patients with delirium and patients without delirium had significant correlation in age, medical disease comorbidity, fracture type, anesthesia method, operation time and perioperative blood loss (P < 0.05). Multivariate logistic regression analysis showed that age (OR = 1.061), preoperative complications (OR = 1.667), perioperative blood loss (OR = 1.002) were positively correlated with postoperative delirium. It shows that older age, more preoperative complications, longer operation time and more perioperative bleeding are more likely to lead to postoperative delirium; patients with general anesthesia were more likely to develop postoperative delirium than patients with local anesthesia (OR = 1.628); and patients with hip and pelvic fractures are more likely to develop a postoperative delirious state (OR = 1.316). Advanced age, complex orthopedic surgery, more medical comorbidities, general anesthesia and greater perioperative blood loss may be independent risk factors for the development of delirium after internal fixation of fractures in middle-aged and elderly patients.
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