Evidence map›Paper›PMID 37563251›Full record

ArticleHandbook of experimental pharmacology2024

Pharmacology of Compounds Targeting Cation-Chloride Cotransporter Physiology.

Eric Delpire, Andrew S Terker, Kenneth B Gagnon

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Handbook of experimental pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Eric DelpireDepartment of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN, USA. eric.delpire@vanderbilt.edu.
Andrew S TerkerDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
Kenneth B GagnonDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Vanderbilt University · USThe University of Texas Southwestern Medical Center · US

Funding

WNK-SPAK signaling in the Distal NephronR01DK093501 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric J Delpire, Paul A Welling · 2012 to 2026
$12.1M
OXGR1 in Renal Intercalated Cells, Salt Transport and Diuretic EfficacyR01DK110375 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric J Delpire, SUSAN MARIE WALL · 2017 to 2026
$6.7M
Innovative therapeutic approaches to treat chronic kidney diseaseDP5OD033412 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TERKER, ANDREW S. · 2022 to 2025
$2.2M
NIDDK NIH HHS R01 DK093501NIDDK NIH HHS R01 DK110375NIH HHS DP5 OD033412
6 · The paper itself

Abstract

Transporters of the solute carrier family 12 (SLC12) carry inorganic cations such as Na

Indexed as

ChloridesSodium-Potassium-Chloride SymportersCationsCryoelectron MicroscopyHumansSolute Carrier Family 12, Member 3CationsChloridesSodium-Potassium-Chloride SymportersSolute Carrier Family 12, Member 3BumetanideCation–chloride cotransportersChloride dyeCryo-EM structureHigh-throughput screeningIon bindingKidneyN-ethylmaleimideNeurodevelopmental disordersProtein–ligand complexThallium dyesThiazide and loop diuretics

Identifiers

PMID37563251
PMCPMC10823342
OpenAlexW4385743704

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.