Evidence map›Paper›PMID 37563144›Full record

ArticleNature communications2023

HIV-1-induced nuclear invaginations mediated by VAP-A, ORP3, and Rab7 complex explain infection of activated T cells.

Mark F Santos, Germana Rappa, Jana Karbanová, Patrizia Diana, Girolamo Cirrincione, Daniela Carbone, David Manna, Feryal Aalam, David Wang, Cheryl Vanier and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Perspectives on the Parathyroid-Thymus Interconnection-A Literature Review.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Molecular regulation of calcium-sensing receptor (CaSR)-mediated signaling.Chronic diseases and translational medicine · 2024
    Review
  10. Article
  11. Coaching ribosome biogenesis from the nuclear periphery.bioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Mark F SantosTouro University Nevada College of Osteopathic Medicine, Henderson, NV, USA.ORCID 0000-0002-6347-8576
Germana RappaTouro University Nevada College of Osteopathic Medicine, Henderson, NV, USA.
Jana KarbanováBiotechnology Center (BIOTEC) and Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0001-7687-0983
Patrizia DianaDepartment of Biological, Chemical, and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Palermo, Italy.
Girolamo CirrincioneDepartment of Biological, Chemical, and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Palermo, Italy.ORCID 0000-0003-0468-625X
Daniela CarboneDepartment of Biological, Chemical, and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Palermo, Italy.ORCID 0000-0001-5969-7023
David MannaTouro College of Osteopathic Medicine, Middletown, New York, NY, USA.
Feryal AalamTouro University Nevada College of Osteopathic Medicine, Henderson, NV, USA.
David WangTouro University Nevada College of Osteopathic Medicine, Henderson, NV, USA.
Cheryl VanierTouro University Nevada College of Osteopathic Medicine, Henderson, NV, USA.ORCID 0000-0003-0497-6150
Denis CorbeilBiotechnology Center (BIOTEC) and Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden, Germany. denis.corbeil@tu-dresden.de.ORCID 0000-0003-1181-3659
Aurelio LoricoTouro University Nevada College of Osteopathic Medicine, Henderson, NV, USA. alorico@touro.edu.
Touro University Nevada · USUniversity of Palermo · ITCenter for Systems Biology Dresden · DERainbow Medical (Israel) · ILTechnische Universität Dresden · DETouro College · US

Funding

Nuclear Transport of Extracellular Vesicle BiomaterialsR15CA252990 · NCI · TOURO UNIVERSITY OF NEVADA · PI LORICO, AURELIO, RAPPA, GERMANA · 2021 to 2021
$275k
NCI NIH HHS R15 CA252990
6 · The paper itself

Abstract

The mechanism of human immunodeficiency virus 1 (HIV-1) nuclear entry, required for productive infection, is not fully understood. Here, we report that in HeLa cells and activated CD4

Indexed as

HIV-1HIV InfectionsCD4-Positive T-LymphocytesGene Products, envHeLa CellsHumansMembrane ProteinsGene Products, envMembrane Proteins

Identifiers

PMID37563144
PMCPMC10415338
OpenAlexW4385720570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.