Evidence map›Paper›PMID 37561962›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2023

High-Temporal/High-Spatial Resolution Breast Magnetic Resonance Imaging Improves Diagnostic Accuracy Compared With Standard Breast Magnetic Resonance Imaging in Patients With High Background Parenchymal Enhancement.

Sarah Eskreis-Winkler, Janice S Sung, Linden Dixon, Natasha Monga, Ragni Jindal, Amber Simmons, Sunitha Thakur, Varadan Sevilimedu, Elizabeth Sutton, Christopher Comstock and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Sarah Eskreis-WinklerDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0003-2427-3532
Janice S SungDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-9067-9840
Linden DixonDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.
Natasha MongaDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.
Ragni JindalDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.
Amber SimmonsWeill Cornell Medical College, New York, NY.
Sunitha ThakurDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0001-8090-3696
Varadan SevilimeduDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
Elizabeth SuttonDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-1407-7012
Christopher ComstockDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.
Kimberly FeiginDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.
Katja PinkerDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-2722-7331
Memorial Sloan Kettering Cancer Center · USCornell University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeTo compare breast magnetic resonance imaging (MRI) diagnostic performance using a standard high-spatial resolution protocol versus a simultaneous high-temporal/high-spatial resolution (HTHS) protocol in women with high levels of background parenchymal enhancement (BPE). MATERIALS AND

methodsWe conducted a retrospective study of contrast-enhanced breast MRIs performed at our institution before and after the introduction of the HTHS protocol. We compared diagnostic performance of the HTHS and standard protocol by comparing cancer detection rate (CDR) and positive predictive value of biopsy (PPV3) among women with high BPE (ie, marked or moderate).

resultsAmong women with high BPE, the HTHS protocol demonstrated increased CDR (23.6 per 1,000 patients

conclusionAmong women with high BPE, HTHS MRI improved diagnostic performance, leading to an additional cancer yield of 15.7 cancers per 1,000 women and concomitantly decreasing unnecessary biopsies by 9.8%. A multisite prospective trial is warranted to confirm these findings and to pave the way for more widespread clinical implementation.

Indexed as

Breast NeoplasmsNeoplasmsBreastFemaleHumansMagnetic Resonance ImagingProspective StudiesRetrospective Studies

Identifiers

PMID37561962
PMCPMC10602549
OpenAlexW4385725146

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.