ArticleACS applied bio materials2023
3D-Printed PEEK/Silicon Nitride Scaffolds with a Triply Periodic Minimal Surface Structure for Spinal Fusion Implants.
Article in ACS applied bio materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Review of surgical methods for stabilizing the lumbosacral spine in dogs with chronic L7-S1 instability.Veterinary research communications · 2025Pooled it
- Polymer Microneedles for Localized Drug Delivery in Musculoskeletal Tissue Regeneration.Journal of functional biomaterials · 2026Review
- Dual reinforcement of PEKK composites with hydroxyapatite and silicon nitride nanowires for enhanced mechanical, tribological, antibacterial, and osteogenic performance.Journal of nanobiotechnology · 2026Article
- 3D Printing of Biopolymer-Based Scaffolds for Bone Tissue Engineering: Materials, Fabrication, and Translational Strategies.Molecules (Basel, Switzerland) · 2026Review
- Stress-driven design of intervertebral disc implants and optimization of mechanical and biological performance.Journal of orthopaedic translation · 2026Article
- Optimization of Silicon Nitride Nanopowder Content in Polyamide 12 (PA12) in Extrusion-Based Additive Manufacturing.Nanomaterials (Basel, Switzerland) · 2025Article
- An Overview of Additive Manufacturing of Triply Periodic Minimal Surface (TPMS) Structures.Polymers · 2025Review
- Hybrid-manufactured silicon nitride coated CFR-PEKK: A candidate biomaterial for trauma plate applications?Journal of the mechanical behavior of biomedical materials · 2025Article
- Transforming spinal surgery with innovations in biologics and additive manufacturing.Materials today. Bio · 2025Review
- Mechanical Characterization of Porous Bone-like Scaffolds with Complex Microstructures for Bone Regeneration.Bioengineering (Basel, Switzerland) · 2025Article
- Understanding the relationship between pore structure and properties of triply periodic minimal surface bone scaffolds.Journal of materials science. Materials in medicine · 2025Review
- Personalized porous tantalum implants crafted via 3D printing: new horizons in complex cervical-thoracic spinal fusion.Frontiers in bioengineering and biotechnology · 2025Article
- Three-dimensional-printed strontium-incorporated β-TCP bioceramic triply periodic minimal surface scaffolds with enhanced angiogenic and osteogenic properties.Regenerative biomaterials · 2025Article
- A Systematic Review of the Contribution of Additive Manufacturing toward Orthopedic Applications.ACS omega · 2024Review
- Personalized bioceramic grafts for craniomaxillofacial bone regeneration.International journal of oral science · 2024Review
- Printability Metrics and Engineering Response of HDPE/SiNanomaterials (Basel, Switzerland) · 2024Article
- Design and study of additively manufactured Three periodic minimal surface (TPMS) structured porous titanium interbody cage.Heliyon · 2024Article
- Article
- Novel 3D printed TPMS scaffolds: microstructure, characteristics and applications in bone regeneration.Journal of tissue engineeringReview
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The issue of spine-related disorders is a global healthcare concern that requires effective solutions to restore normal spine functioning. Spinal fusion implants have become a standard approach for this purpose, making it crucial to develop biomaterials and structures that possess high osteogenic capacities and exhibit mechanical properties and dynamic responses similar to those of the host bone. This study focused on the fabrication of 3D-printed polyether ether ketone/silicon nitride (PEEK/SiN) scaffolds with a triply periodic minimal surface (TPMS) structure, which offers several advantages, such as a large surface area and uniform stress distribution under load. The mechanical properties and dynamic response of PEEK/SiN scaffolds with varying porosities were evaluated through mechanical testing and finite element analysis. The scaffold with 30% porosity exhibited a compressive strength (34.56 ± 1.91 MPa) and elastic modulus (734 ± 64 MPa) similar to those of trabecular bone. In addition, the scaffold demonstrated favorable damping properties. The biological data revealed that incorporating silicon nitride into the PEEK scaffold stimulated osteogenic differentiation. In light of these findings, it can be inferred that PEEK/SiN TPMS scaffolds exhibit significant potential for use in bone tissue engineering and represent a promising option as candidates for spinal fusion implants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.