Evidence map›Paper›PMID 37561870›Full record

ArticleScience (New York, N.Y.)2023

Bioadhesive polymer semiconductors and transistors for intimate biointerfaces.

Nan Li, Yang Li, Zhe Cheng, Youdi Liu, Yahao Dai, Seounghun Kang, Songsong Li, Naisong Shan, Shinya Wai, Aidan Ziaja and 8 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Nan LiPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-6818-035X
Yang LiPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0003-1912-1438
Zhe ChengDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.
Youdi LiuPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.
Yahao DaiPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-6393-5514
Seounghun KangPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.ORCID 0009-0005-2492-2995
Songsong LiPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-9784-2877
Naisong ShanPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-1476-6539
Shinya WaiPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-8973-1923
Aidan ZiajaPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.
Yunfei WangSchool of Polymer Science and Engineering, University of Southern Mississippi, Hattiesburg, MS 39406, USA.ORCID 0000-0001-7555-5308
Joseph StrzalkaX-Ray Science Division, Argonne National Laboratory, Lemont, IL 60439, USA.ORCID 0000-0003-4619-8932
Wei LiuPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-1207-204X
Cheng ZhangPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0003-3026-1159
Xiaodan GuSchool of Polymer Science and Engineering, University of Southern Mississippi, Hattiesburg, MS 39406, USA.ORCID 0000-0002-1123-3673
Jeffrey A HubbellPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0003-0276-5456
Bozhi TianDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0003-0593-0023
Sihong WangPritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-3611-0004

Funding

Immunocompatible electronic polymers and devices for implantable sensors and stimulators that resist foreign-body responsesDP2EB034563 · NIBIB · UNIVERSITY OF CHICAGO · PI WANG, SIHONG · 2022 to 2025
$2.3M
NIBIB NIH HHS DP2 EB034563
6 · The paper itself

Abstract

The use of bioelectronic devices relies on direct contact with soft biotissues. For transistor-type bioelectronic devices, the semiconductors that need to have direct interfacing with biotissues for effective signal transduction do not adhere well with wet tissues, thereby limiting the stability and conformability at the interface. We report a bioadhesive polymer semiconductor through a double-network structure formed by a bioadhesive brush polymer and a redox-active semiconducting polymer. The resulting semiconducting film can form rapid and strong adhesion with wet tissue surfaces together with high charge-carrier mobility of ~1 square centimeter per volt per second, high stretchability, and good biocompatibility. Further fabrication of a fully bioadhesive transistor sensor enabled us to produce high-quality and stable electrophysiological recordings on an isolated rat heart and in vivo rat muscles.

Indexed as

PolymersSemiconductorsTissue AdhesivesTransistors, ElectronicAnimalsElectrophysiological PhenomenaHeartMuscle, SkeletalRatsPolymersTissue Adhesives

Identifiers

PMID37561870
PMCPMC10768720

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.