Evidence map›Paper›PMID 37561373›Full record

ArticleBulletin of experimental biology and medicine2023

The Neurotoxic Effect of β-Amyloid Is Accompanied by Changes in the Mitochondrial Dynamics and Autophagy in Neurons and Brain Endothelial Cells in the Experimental Model of Alzheimer's Disease.

A S Averchuk, M V Ryazanova, T I Baranich, A V Stavrovskaya, N A Rozanova, S V Novikova, A B Salmina

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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  7. Article
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  9. Article
  10. Mitochondria in Alzheimer's Disease Pathogenesis.Life (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

A S AverchukResearch Center of Neurology, Moscow, Russia. antonaverchuk@yandex.ru.
M V RyazanovaResearch Center of Neurology, Moscow, Russia.
T I BaranichResearch Center of Neurology, Moscow, Russia.
A V StavrovskayaResearch Center of Neurology, Moscow, Russia.
N A RozanovaResearch Center of Neurology, Moscow, Russia.
S V NovikovaResearch Center of Neurology, Moscow, Russia.
A B SalminaResearch Center of Neurology, Moscow, Russia.
Research Center of Neurology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A comparative assessment of the expression of the mitochondrial fission marker Drp1 and the autophagy marker LC3 in neurons and endothelial cells in the hippocampus and entorhinal cortex during progression of cognitive deficit was performed in animals with intrahippocampal administration of β-amyloid. In both brain regions, the expression of Drp1 and LC3 in neuronal and endothelial cells was enhanced. The peak of cognitive impairment corresponded to the maximum expression of Drp1 and LC3 in hippocampal neurons and was preceded by an increase in the number of Drp1

Indexed as

Alzheimer DiseaseAutophagyBrainMitochondriaNeuronsAmyloid beta-Protein PrecursorAnimalsDisease Models, AnimalEndothelial CellsMiceMice, Inbred C57BLAmyloid beta-Protein PrecursorAlzheimer’s diseaseautophagyendotheliocytehippocampusneurons

Identifiers

PMID37561373
OpenAlexW4385716028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.