Evidence map›Paper›PMID 37561363›Full record

ReviewMedical oncology (Northwood, London, England)2023

Liquid biopsy in ovarian cancer: advantages and limitations for prognosis and diagnosis.

Farzaneh Karimi, Omid Azadbakht, Ali Veisi, Mohammad Sabaghan, Maryam Owjfard, Ebrahim Kharazinejad, Negar Dinarvand

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical oncology (Northwood, London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Farzaneh KarimiDepartment of Physiology, Behbahan Faculty of Medical Sciences, Behbahan, Iran. karimifarzaneh502@gmail.com.ORCID http://orcid.org/0000-0002-1512-7333
Omid AzadbakhtDepartment of Radiology Technology, Behbahan Faculty of Medical Sciences, Behbahan, Iran.ORCID http://orcid.org/0000-0003-1272-4121
Ali VeisiDepartment of Physiology, Behbahan Faculty of Medical Sciences, Behbahan, Iran.ORCID http://orcid.org/0000-0001-7608-603X
Mohammad SabaghanDepartment of Parasitology, Behbahan Faculty of Medical Sciences, Behbahan, Iran.ORCID http://orcid.org/0000-0003-4670-767X
Maryam OwjfardClinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ebrahim KharazinejadDepartment of Anatomy, Abadan University of Medical Sciences, Abadan, Iran.
Negar DinarvandHyperlipidemia Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.ORCID http://orcid.org/0000-0002-8025-7548
Ahvaz Jundishapur University of Medical Sciences · IRHamedan University of Medical Sciences · IRIsfahan University of Medical Sciences · IRShiraz University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer (OC) is a highly fatal gynecologic malignancy, often diagnosed at an advanced stage which presents significant challenges for disease management. The clinical application of conventional tissue biopsy methods and serological biomarkers has limitations for the diagnosis and prognosis of OC patients. Liquid biopsy is a novel sampling method that involves analyzing distinctive tumor elements secreted into the peripheral blood. Growing evidence suggests that liquid biopsy methods such as circulating tumor cells, cell-free RNA, circulating tumor DNA, exosomes, and tumor-educated platelets may improve early prognosis and diagnosis of OC, leading to enhanced therapeutic management of the disease. This study reviewed the evidence demonstrating the utility of liquid biopsy components in OC prognosis and diagnosis, and evaluated the current advantages and limitations of these methods. Additionally, the existing obstacles and crucial topics for future studies utilizing liquid biopsy in OC patients were discussed.

Indexed as

ExosomesNeoplastic Cells, CirculatingOvarian NeoplasmsBiomarkers, TumorDNA, NeoplasmFemaleHumansLiquid BiopsyPrognosisBiomarkers, TumorDNA, NeoplasmDiagnosisExtracellular vesiclesLiquid biopsyOvarian cancerPrognosis

Identifiers

PMID37561363
OpenAlexW4385716625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.