Evidence map›Paper›PMID 37561144›Full record

SynthesisEuropean journal of nuclear medicine and molecular imaging2023

Positron emission tomography in the diagnosis and follow-up of transthyretin amyloid cardiomyopathy patients: A systematic review.

H S A Tingen, A Tubben, J H van 't Oever, E M Pastoor, P P A van Zon, H L A Nienhuis, P van der Meer, R H J A Slart

Erratum issuedAbstract readSystematic Review
In one paragraph

Synthesis in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Collection on molecular imaging in cardiac amyloidosis.European journal of nuclear medicine and molecular imaging · 2024
    Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

H S A TingenDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands. h.s.a.tingen@umcg.nl.ORCID 0000-0002-8572-9428
A TubbenAmyloidosis Centre of Expertise, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.ORCID 0000-0001-8414-958X
J H van 't OeverAmyloidosis Centre of Expertise, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.ORCID 0009-0005-7666-1280
E M PastoorAmyloidosis Centre of Expertise, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.ORCID 0009-0002-3319-5484
P P A van ZonAmyloidosis Centre of Expertise, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.ORCID 0009-0009-9070-8080
H L A NienhuisAmyloidosis Centre of Expertise, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.ORCID 0000-0003-3974-6830
P van der MeerAmyloidosis Centre of Expertise, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.ORCID 0000-0002-9705-4413
R H J A SlartDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.ORCID 0000-0002-5565-1164

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTransthyretin (ATTR) amyloidosis is a progressive protein misfolding disease with frequent cardiac involvement. This review aims to determine the value of PET in diagnosis, assessment of disease progression or treatment response and its relation to clinical outcome in follow-up of ATTR amyloid cardiomyopathy (ATTR-CM) patients.

methodsMedline, Cochrane Library, Embase and Web of Science databases were searched, from the earliest date available until December 2022, for studies investigating the use of PET in ATTR-CM patients. Studies containing original data were included, except for case reports. Risk of bias was assessed by QUADAS-2.

resultsTwenty-one studies were included in this systematic review, investigating five different tracers: carbon-11 Pittsburgh compound B ([

conclusion[

Indexed as

AmyloidosisCardiomyopathiesFluorine RadioisotopesFollow-Up StudiesHumansPositron-Emission TomographyPrealbuminFluorine-18Fluorine RadioisotopesPrealbuminATTRcardiomyopathydiagnostic accuracymonitoring therapyPET

Identifiers

PMID37561144
PMCPMC10684414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.