Evidence map›Paper›PMID 37560745›Full record

ArticleArchives of medical science : AMS2023

The role of nutraceuticals in heart failure muscle wasting as a result of inflammatory activity. The International Lipid Expert Panel (ILEP) Position Paper.

Agata Bielecka-Dabrowa, Maciej Banach, Andrzej Wittczak, Arrigo F G Cicero, Amani Kallel, Raimondas Kubilius, Dimitri P Mikhailidis, Amirhossein Sahebkar, Anca Pantea Stoian, Dragos Vinereanu and 2 more

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Atherosclerotic features in patients with heart failure.Archives of medical science : AMS · 2025
    Article
  5. Gut microbiota and arterial hypertension: a narrative review.Archives of medical science : AMS · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The year in nutrition medicine 2023.Archives of medical science : AMS · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Agata Bielecka-DabrowaDepartment of Preventive Cardiology and Lipidology, Medical University of Lodz (MUL), Lodz, Poland.
Maciej BanachDepartment of Preventive Cardiology and Lipidology, Medical University of Lodz (MUL), Lodz, Poland.
Andrzej WittczakDepartment of Preventive Cardiology and Lipidology, Medical University of Lodz (MUL), Lodz, Poland.
Arrigo F G CiceroIRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Amani KallelUniversity of Tunis El Manar, Faculty of Medicine of Tunis, Tunis, Tunisia.
Raimondas KubiliusDepartment of Rehabilitation, Hospital of Lithuanian University of Health Sciences Kauno Klinikos, Kaunas, Lithuania.
Dimitri P MikhailidisDepartment of Surgical Biotechnology, Division of Surgery and Interventional Science, University College London Medical School, University College London (UCL) and Department of Clinical Biochemistry, Royal Free Hospital Campus, UCL, London, UK.
Amirhossein SahebkarApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Anca Pantea StoianFaculty of Medicine, Diabetes, Nutrition and Metabolic Diseases, Carol Davila University, Bucharest, Romania.
Dragos VinereanuUniversity Emergency Hospital of Bucharest, Bucharest, Romania.
Peter E PensonClinical Pharmacy and Therapeutics Research Group, School of Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.
Stephan von HaehlingDepartment of Cardiology and Pneumology, University Medical Center Göttingen (UMG), Göttingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscle wasting is one of the main causes for exercise intolerance and ventilatory inefficiency in patients with heart failure and a strong predictor of frailty and reduced survival. The prevalence of sarcopenia is at least 20% in patients with heart failure. Patients with heart failure often have subclinical systemic inflammation, which may exert sustained effects on skeletal muscle. Besides exercise, nutrition should also be carefully evaluated as an appropriate diet with selected nutraceuticals may be able to stimulate muscle anabolism and inhibit muscle catabolism. This review summarizes the epidemiological and clinical trial evidence supporting the recommendations for the use of nutraceuticals with anti-inflammatory properties in heart failure and provides an overview of the state of the evidence for nutraceutical supplementation to prevent and/or mitigate heart failure muscle wasting.

Indexed as

hand grip strengthheart failureinflammationmuscle wastingnutraceuticalssarcopenia

Identifiers

PMID37560745
PMCPMC10408027

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.