Evidence map›Paper›PMID 37560527›Full record

ArticleFrontiers in microbiology2023

Microbial signature of intestine in children with allergic rhinitis.

Panpan Zhang, Xuehua Zhou, Hong Tan, Fangfang Jian, Zenghui Jing, Huajie Wu, Yao Zhang, Jianfeng Luo, Juan Zhang, Xin Sun

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Panpan ZhangDepartment of Pediatrics, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Xuehua ZhouDepartment of Pediatrics, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Hong TanDepartment of Pediatrics, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Fangfang JianDepartment of Pediatrics, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Zenghui JingDepartment of Pediatrics, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Huajie WuDepartment of Pediatrics, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Yao ZhangDepartment of Pediatrics, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Jianfeng LuoDepartment of Pediatrics, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Juan ZhangDepartment of Pediatrics, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Xin SunDepartment of Pediatrics, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Previous studies have found that unique patterns of gut microbial colonization in infancy associated with the development of allergic diseases. However, there is no research on the gut microbiota characteristics of AR children in Chinese Mainland. Objective: To investigate the changes of gut microbial of AR children in Chinese Mainland and evaluate the correlation between gut microbial and clinical indexes. Methods: In this clinical study, fecal samples from 24 AR children and 25 healthy control children (HCs) were comparative via next generation sequencing of the V3-V4 regions of the 16S rRNA gene. Analyzed the relationship between clinical features and gut microbial using Spearman correlation. Results: Compared to HCs, AR children showed significant decreases in Shannon index and significant increases in Simpson index at both the family and genera levels (all Conclusion: AR children in Chinese Mainland were characterized by reduced microbial diversity and distinguished microbial characteristics in comparison with HCs. The observations of this study offer proof that distinctive gut microbiota profiles were present in AR children and necessitate further investigation in the form of mechanistic studies.

Indexed as

16S rRNA gene sequencingallergic rhinitischildrengutmicrobiota

Identifiers

PMID37560527
PMCPMC10408450

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.