Evidence map›Paper›PMID 37560478›Full record

ArticleInternational journal of clinical and health psychology : IJCHP

Neuroanatomical and functional substrates of the hypomanic personality trait and its prediction on aggression.

Wenwei Zhu, Xiongying Chen, Jie Wu, Zixi Li, Hohjin Im, Shuning Chen, Kun Deng, Bin Zhang, Chuqiao Wei, Junjiao Feng and 4 more

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In one paragraph

Article in International journal of clinical and health psychology : IJCHP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Wenwei ZhuFaculty of Psychology, Tianjin Normal University, Tianjin 300387, China.
Xiongying ChenThe National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China.
Jie WuFaculty of Psychology, Tianjin Normal University, Tianjin 300387, China.
Zixi LiFaculty of Psychology, Tianjin Normal University, Tianjin 300387, China.
Hohjin ImDepartment of Psychological Science, University of California, Irvine, CA 92697-7085, USA.
Shuning ChenFaculty of Psychology, Tianjin Normal University, Tianjin 300387, China.
Kun DengFaculty of Psychology, Tianjin Normal University, Tianjin 300387, China.
Bin ZhangFaculty of Psychology, Tianjin Normal University, Tianjin 300387, China.
Chuqiao WeiFaculty of Psychology, Tianjin Normal University, Tianjin 300387, China.
Junjiao FengFaculty of Psychology, Tianjin Normal University, Tianjin 300387, China.
Manman ZhangFaculty of Psychology, Tianjin Normal University, Tianjin 300387, China.
Shaofeng YangFaculty of Psychology, Tianjin Normal University, Tianjin 300387, China.
He WangInstitute of Biomedical Engineering, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300192, China.
Qiang WangFaculty of Psychology, Tianjin Normal University, Tianjin 300387, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypomanic personality manifests a close link with several psychiatric disorders and its abnormality is a risk indicator for developing bipolar disorders. We systematically investigated the potential neuroanatomical and functional substrates underlying hypomanic personality trait (HPT) and its sub-dimensions (i.e., Social Vitality, Mood Volatility, and Excitement) combined with structural and functional imaging data as well as their corresponding brain networks in a large non-clinical sample across two studies (n = 464). Behaviorally, HPT, specifically Mood Volatility and Excitement, was positively associated with aggressive behaviors in both studies. Structurally, sex-specific morphological characteristics were further observed in the motor and top-down control networks especially for Mood Volatility, although HPT was generally positively associated with grey matter volumes (GMVs) in the prefrontal, temporal, visual, and limbic systems. Functionally, brain activations related to immediate or delayed losses were found to predict individual variability in HPT, specifically Social Vitality and Excitement, on the motor and prefrontal-parietal cortices. Topologically, connectome-based prediction model analysis further revealed the predictive role of individual-level morphological and resting-state functional connectivity on HPT and its sub-dimensions, although it did not reveal any links with general brain topological properties. GMVs in the temporal, limbic (e.g., amygdala), and visual cortices mediated the effects of HPT on behavioral aggression. These findings suggest that the imbalance between motor and control circuits may be critical for HPT and provide novel insights into the neuroanatomical, functional, and topological mechanisms underlying the specific temperament and its impacts on aggression.

Indexed as

AggressionConnectome-based prediction modelGraph theoryHypomanic personality traitVoxel-based morphometry

Identifiers

PMID37560478
PMCPMC10407439

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.