Evidence map›Paper›PMID 37560122›Full record

ArticleComputational and structural biotechnology journal2023

Resolving the role of podoplanin in the motility of papillary thyroid carcinoma-derived cells using RNA sequencing.

Damian Mielecki, Ewa Gajda, Justyna Sikorska, Anna Betkowska, Marcin Rozwadowski, Agata M Gawel, Maria Kulecka, Natalia Zeber-Lubecka, Marlena Godlewska, Damian Gawel

Abstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Damian MieleckiCentre of Postgraduate Medical Education, Department of Cell Biology and Immunology, Marymoncka 99/103, 01-813 Warsaw, Poland.
Ewa GajdaCentre of Postgraduate Medical Education, Department of Cell Biology and Immunology, Marymoncka 99/103, 01-813 Warsaw, Poland.
Justyna SikorskaCentre of Postgraduate Medical Education, Department of Cell Biology and Immunology, Marymoncka 99/103, 01-813 Warsaw, Poland.
Anna BetkowskaCentre of Postgraduate Medical Education, Department of Cell Biology and Immunology, Marymoncka 99/103, 01-813 Warsaw, Poland.
Marcin RozwadowskiCentre of Postgraduate Medical Education, Department of Cell Biology and Immunology, Marymoncka 99/103, 01-813 Warsaw, Poland.
Agata M GawelMedical University of Warsaw, Histology and Embryology Students Science Association at the Department for Histology and Embryology, Chalubinskiego 5, 02-004 Warsaw, Poland.
Maria KuleckaCentre of Postgraduate Medical Education, Department of Gastroenterology, Hepatology and Clinical Oncology, Marymoncka 99/103, 01-813 Warsaw, Poland.
Natalia Zeber-LubeckaCentre of Postgraduate Medical Education, Department of Gastroenterology, Hepatology and Clinical Oncology, Marymoncka 99/103, 01-813 Warsaw, Poland.
Marlena GodlewskaCentre of Postgraduate Medical Education, Department of Cell Biology and Immunology, Marymoncka 99/103, 01-813 Warsaw, Poland.
Damian GawelCentre of Postgraduate Medical Education, Department of Cell Biology and Immunology, Marymoncka 99/103, 01-813 Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intracellular level of podoplanin (PDPN), a transmembrane protein of still unclear function, is frequently altered in metastatic tumors. High expression of PDPN is frequently observed in papillary thyroid cancer (PTC) specimens. Similarly, PTC-derived cell lines (BCPAP and TPC1, harboring the

Indexed as

ARHGAPARHGEFBRAF V600ELamellipodiaMetastasisMigrationPapillary thyroid carcinomaPodoplaninRAC1RHOARNA seqencing

Identifiers

PMID37560122
PMCPMC10407544

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.