Evidence map›Paper›PMID 37560017›Full record

ArticleHorticulture research2023

quarTeT: a telomere-to-telomere toolkit for gap-free genome assembly and centromeric repeat identification.

Yunzhi Lin, Chen Ye, Xingzhu Li, Qinyao Chen, Ying Wu, Feng Zhang, Rui Pan, Sijia Zhang, Shuxia Chen, Xu Wang and 5 more

Abstract read
In one paragraph

Article in Horticulture research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 263 papers.

0numbers the graph read from it
0cells of the map it votes in
263citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

263 citing papers in PubMed.

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  8. Telomere-to-telomere genome ofHorticulture research · 2026
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203 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

15 authors.

Yunzhi LinCollege of Life Science, Sichuan University, Chengdu, Sichuan 610064, China.ORCID https://orcid.org/0000-0001-8425-2552
Chen YeSchool of Information and Computer, Anhui Agricultural University, Hefei, Anhui 230036, China.
Xingzhu LiSchool of Horticulture, Anhui Agricultural University, Hefei, Anhui 230036, China.
Qinyao ChenSchool of Horticulture, Anhui Agricultural University, Hefei, Anhui 230036, China.
Ying WuSchool of Horticulture, Anhui Agricultural University, Hefei, Anhui 230036, China.
Feng ZhangSchool of Horticulture, Anhui Agricultural University, Hefei, Anhui 230036, China.
Rui PanSchool of Horticulture, Anhui Agricultural University, Hefei, Anhui 230036, China.
Sijia ZhangSchool of Horticulture, Anhui Agricultural University, Hefei, Anhui 230036, China.
Shuxia ChenSchool of Information and Computer, Anhui Agricultural University, Hefei, Anhui 230036, China.
Xu WangAgricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong 518124, China.
Shuo CaoAgricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong 518124, China.
Yingzhen WangSchool of Horticulture, Anhui Agricultural University, Hefei, Anhui 230036, China.
Yi YueSchool of Information and Computer, Anhui Agricultural University, Hefei, Anhui 230036, China.
Yongsheng LiuCollege of Life Science, Sichuan University, Chengdu, Sichuan 610064, China.
Junyang YueSchool of Horticulture, Anhui Agricultural University, Hefei, Anhui 230036, China.ORCID https://orcid.org/0000-0002-5299-0160

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A high-quality genome is the basis for studies on functional, evolutionary, and comparative genomics. The majority of attention has been paid to the solution of complex chromosome structures and highly repetitive sequences, along with the emergence of a new 'telomere-to-telomere (T2T) assembly' era. However, the bioinformatic tools for the automatic construction and/or characterization of T2T genome are limited. Here, we developed a user-friendly web toolkit, quarTeT, which currently includes four modules: AssemblyMapper, GapFiller, TeloExplorer, and CentroMiner. First, AssemblyMapper is designed to assemble phased contigs into the chromosome-level genome by referring to a closely related genome. Then, GapFiller would endeavor to fill all unclosed gaps in a given genome with the aid of additional ultra-long sequences. Finally, TeloExplorer and CentroMiner are applied to identify candidate telomere and centromere as well as their localizations on each chromosome. These four modules can be used alone or in combination with each other for T2T genome assembly and characterization. As a case study, by adopting the entire modular functions of quarTeT, we have achieved the

Identifiers

PMID37560017
PMCPMC10407605

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.