Evidence map›Paper›PMID 37559573›Full record

ArticleOncology letters2023

Monocyte subsets associated with the efficacy of anti‑PD‑1 antibody monotherapy.

Ryotaro Ohkuma, Yuki Fujimoto, Katsuaki Ieguchi, Nobuyuki Onishi, Makoto Watanabe, Daisuke Takayanagi, Tsubasa Goshima, Atsushi Horiike, Kazuyuki Hamada, Hirotsugu Ariizumi and 14 more

Abstract read
In one paragraph

Article in Oncology letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Ryotaro OhkumaDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Yuki FujimotoDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Katsuaki IeguchiDepartment of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Tokyo 157-8577, Japan.
Nobuyuki OnishiDepartment of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Tokyo 157-8577, Japan.
Makoto WatanabeDepartment of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Tokyo 157-8577, Japan.
Daisuke TakayanagiDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Tsubasa GoshimaDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Atsushi HoriikeDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Kazuyuki HamadaDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Hirotsugu AriizumiDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Yuya HirasawaDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Tomoyuki IshiguroDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Risako SuzukiDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Nana IriguchiDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Toshiaki TsuruiDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Yosuke SasakiDepartment of Pathology, Showa University School of Medicine, Tokyo 157-8577, Japan.
Mayumi HommaDepartment of Pathology, Showa University School of Medicine, Tokyo 157-8577, Japan.
Toshiko YamochiDepartment of Pathology, Showa University School of Medicine, Tokyo 157-8577, Japan.
Kiyoshi YoshimuraDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Mayumi TsujiDivision of Medical Pharmacology, Department of Pharmacology, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Yuji KiuchiDivision of Medical Pharmacology, Department of Pharmacology, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Shinichi KobayashiClinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Tokyo 157-8577, Japan.
Takuya TsunodaDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.
Satoshi WadaDivision of Medical Oncology, Department of Medicine, School of Medicine, Showa University, Tokyo 142-8555, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune checkpoint inhibitors (ICIs) are among the most notable advances in cancer immunotherapy; however, reliable biomarkers for the efficacy of ICIs are yet to be reported. Programmed death (PD)-ligand 1 (L1)-expressing CD14

Indexed as

anti-programmed death-1 antibodybiomarkercancer immunotherapyclassical monocytesimmune checkpoint inhibitorsmonocyte subsetsnon-classical monocytesprogrammed death-ligand 1

Identifiers

PMID37559573
PMCPMC10407861

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.