Evidence map›Paper›PMID 37559241›Full record

ReviewCurrent pharmaceutical design2024

Medicinal Plant-derived Phytochemicals in Detoxification.

Geir Bjørklund, Natália Cruz-Martins, Bey Hing Goh, Olha Mykhailenko, Roman Lysiuk, Mariia Shanaida, Larysa Lenchyk, Taras Upyr, Marius Emil Rusu, Antonina Pryshlyak and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pharmaceutical design, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Geir BjørklundDepartment of Research, Council for Nutritional and Environmental Medicine (CONEM), Toften 24, Mo i Rana 8610, Norway.
Natália Cruz-MartinsFaculty of Medicine, University of Porto, Alameda Prof. Hernani Monteiro, Porto, Portugal.
Bey Hing GohBiofunctional Molecule Exploratory (BMEX) Research Group, School of Pharmacy, Monash University Malaysia, Victoria, Malaysia.
Olha MykhailenkoDepartment of Pharmaceutical Chemistry, National University of Pharmacy of Ministry of Health of Ukraine, Kharkiv, Ukraine.
Roman LysiukDepartment of Pharmacognosy and Botany, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.
Mariia ShanaidaDepartment of Pharmacognosy and Medical Botany, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.
Larysa LenchykCONEM Ukraine Pharmacognosy and Natural Product Chemistry Research Group, National University of Pharmacy, Kharkiv, Ukraine.
Taras UpyrCONEM Ukraine Pharmacognosy and Natural Product Chemistry Research Group, National University of Pharmacy, Kharkiv, Ukraine.
Marius Emil RusuDepartment of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Antonina PryshlyakDepartment of Human Anatomy, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.
Volodymyr ShanaidaDesign of Machine Tools, Instruments and Machines Department, Ternopil Ivan Puluj National Technical University, Ternopil, Ukraine.
Salvatore ChirumboloDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The average worldwide human life expectancy is 70 years, with a significantly higher value in Western societies. Many modern diseases are not associated with premature mortality but with a decreased quality of life in aged patients and an excessive accumulation of various toxic compounds in the human body during life. Today, scientists are especially interested in finding compounds that can help increase a healthy lifespan by detoxifying the body. Phytotherapy with specific approaches is used in alternative medicine to remove toxins from the body. Worldwide, research is conducted to identify medicinal plant-derived molecules that, with few or no side effects, may protect the liver and other organs. This review provides updated information about the detoxification process, the traditional and modern use of the most effective medicinal plants, their active metabolites as detoxifying agents, and the mechanisms and pathways involved in the detoxification process. Among medicinal plants with substantial detoxifying properties, a major part belongs to the

Indexed as

PhytochemicalsPlants, MedicinalAnimalsHumansInactivation, MetabolicPhytotherapyPhytochemicalsbioactive natural compoundsdetoxifying agentshepatoprotectionmechanisms of action.Medicinal plantsphytotherapy

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.