Evidence map›Paper›PMID 37559062›Full record

SynthesisBMC medical informatics and decision making2023

The accuracy of artificial intelligence in predicting COVID-19 patient mortality: a systematic review and meta-analysis.

Yu Xin, Hongxu Li, Yuxin Zhou, Qing Yang, Wenjing Mu, Han Xiao, Zipeng Zhuo, Hongyu Liu, Hongying Wang, Xutong Qu and 3 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC medical informatics and decision making, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yu Xin *Department of Critical Care Medicine, the First Affiliated Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang Province, China.
Hongxu Li *Department of Critical Care Medicine, the First Affiliated Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang Province, China.
Yuxin Zhou *Department of Critical Care Medicine, the First Affiliated Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang Province, China.
Qing Yang *Department of Critical Care Medicine, Harbin Medical University Cancer Hospital, No. 150 Haping Rd, Nangang District, Harbin, 150081, China.
Wenjing MuDepartment of Critical Care Medicine, Harbin Medical University Cancer Hospital, No. 150 Haping Rd, Nangang District, Harbin, 150081, China.
Han XiaoDepartments of Pharmacy and Cardiology, Harbin Medical University Cancer Hospital, No. 150 Haping Rd, Nangang District, Harbin, 150081, China.
Zipeng ZhuoDepartment of Critical Care Medicine, Harbin Medical University Cancer Hospital, No. 150 Haping Rd, Nangang District, Harbin, 150081, China.
Hongyu LiuDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, No. 150 Haping Rd, Nangang District, Harbin, 150081, China.
Hongying WangDepartment of Critical Care Medicine, Harbin Medical University Cancer Hospital, No. 150 Haping Rd, Nangang District, Harbin, 150081, China.
Xutong QuDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, No. 150 Haping Rd, Nangang District, Harbin, 150081, China.
Changsong WangDepartment of Critical Care Medicine, the First Affiliated Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang Province, China. changsongwangicu@163.com.
Haitao LiuDepartment of Critical Care Medicine, Harbin Medical University Cancer Hospital, No. 150 Haping Rd, Nangang District, Harbin, 150081, China. dr633@163.com.
Kaijiang YuDepartment of Critical Care Medicine, the First Affiliated Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang Province, China. drkaijiang@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this paper was to systematically evaluate the application value of artificial intelligence in predicting mortality among COVID-19 patients.

methodsThe PubMed, Embase, Web of Science, CNKI, Wanfang, China Biomedical Literature, and VIP databases were systematically searched from inception to October 2022 to identify studies that evaluated the predictive effects of artificial intelligence on mortality among COVID-19 patients. The retrieved literature was screened according to the inclusion and exclusion criteria. The quality of the included studies was assessed using the QUADAS-2 tools. Statistical analysis of the included studies was performed using Review Manager 5.3, Stata 16.0, and Meta-DiSc 1.4 statistical software. This meta-analysis was registered in PROSPERO (CRD42022315158).

findingsOf 2193 studies, 23 studies involving a total of 25 AI models met the inclusion criteria. Among them, 18 studies explicitly mentioned training and test sets, and 5 studies did not explicitly mention grouping. In the training set, the pooled sensitivity was 0.93 [0.87, 0.96], the pooled specificity was 0.94 [0.87, 0.97], and the area under the ROC curve was 0.98 [0.96, 0.99]. In the validation set, the pooled sensitivity was 0.84 [0.78, 0.88], the pooled specificity was 0.89 [0.85, 0.92], and the area under the ROC curve was 0.93 [1.00, 0.00]. In the subgroup analysis, the areas under the summary receiver operating characteristic (SROC) curves of the artificial intelligence models KNN, SVM, ANN, RF and XGBoost were 0.98, 0.98, 0.94, 0.92, and 0.91, respectively. The Deeks funnel plot indicated that there was no significant publication bias in this study (P > 0.05).

interpretationArtificial intelligence models have high accuracy in predicting mortality among COVID-19 patients and have high prognostic value. Among them, the KNN, SVM, ANN, RF, XGBoost, and other models have the highest levels of accuracy.

Indexed as

Artificial IntelligenceCOVID-19ChinaHumansROC CurveSensitivity and SpecificityArtificial intelligenceCOVID-19meta-analysisMortality

Identifiers

PMID37559062
PMCPMC10410953

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.