Evidence map›Paper›PMID 37558865›Full record

ReviewCurrent medical science2023

Research Progress in Function and Regulation of E3 Ubiquitin Ligase SMURF1.

Ji-Xi Wan, Yu-Qi Wang, Si-Na Lan, Liu Chen, Ming-Qian Feng, Xin Chen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ji-Xi Wan *College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Yu-Qi Wang *College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Si-Na LanCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Liu ChenCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Ming-Qian FengCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Xin ChenCollege of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China. chenxin1990@webmail.hzau.edu.cn.
Huazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Smad ubiquitylation regulatory factor 1 (Smurf1) is an important homologous member of E6-AP C-terminus type E3 ubiquitin ligase. Initially, Smurf1 was reportedly involved in the negative regulation of the bone morphogenesis protein (BMP) pathway. After further research, several studies have confirmed that Smurf1 is widely involved in various biological processes, such as bone homeostasis regulation, cell migration, apoptosis, and planar cell polarity. At the same time, recent studies have provided a deeper understanding of the regulatory mechanisms of Smurf1's expression, activity, and substrate selectivity. In our review, a brief summary of recent important biological functions and regulatory mechanisms of E3 ubiquitin ligase Smurf1 is proposed.

Indexed as

Ubiquitin-Protein LigasesAnimalsApoptosisBone Morphogenetic ProteinsCell MovementCell PolarityHumansSignal TransductionUbiquitinationBone Morphogenetic ProteinsSMURF1 protein, humanUbiquitin-Protein Ligasesbone homeostasisbone morphogenesis protein signalingcancerE3 ubiquitin ligasenerve cell developmentSmad ubiquitination regulator 1

Identifiers

PMID37558865
OpenAlexW4385715551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.