Evidence map›Paper›PMID 37558673›Full record

ArticleNPJ vaccines2023

Multifunctional IgG/IgM antibodies and cellular cytotoxicity are elicited by the full-length MSP1 SumayaVac-1 malaria vaccine.

Micha Rosenkranz, Kristin Fürle, Julia Hibbert, Anne Ulmer, Arin Ali, Thomas Giese, Antje Blank, Walter E Haefeli, Ernst Böhnlein, Michael Lanzer and 1 more

Open access · goldAbstract read
In one paragraph

Article in NPJ vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. An mRNA-lipid nanoparticle vaccine targeting theMolecular therapy. Nucleic acids · 2026
    Article
  2. Genetic Diversity and Allelic Distribution ofJournal of parasitology research · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Micha Rosenkranz *Center for Infectious Diseases-Parasitology, Heidelberg University Hospital, Heidelberg, Germany.
Kristin Fürle *Center for Infectious Diseases-Parasitology, Heidelberg University Hospital, Heidelberg, Germany.
Julia HibbertCenter for Infectious Diseases-Parasitology, Heidelberg University Hospital, Heidelberg, Germany.
Anne UlmerCenter for Infectious Diseases-Parasitology, Heidelberg University Hospital, Heidelberg, Germany.
Arin AliCenter for Infectious Diseases-Parasitology, Heidelberg University Hospital, Heidelberg, Germany.
Thomas GieseInstitute for Immunology, Heidelberg University Hospital and German Center for Infection Research (DZIF), Heidelberg, Germany.
Antje BlankClinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-8743-5194
Walter E HaefeliClinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany.
Ernst BöhnleinSumaya-Biotech GmbH & Co. KG, Heidelberg, Germany.
Michael LanzerCenter for Infectious Diseases-Parasitology, Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-0220-6526
Richard Thomson-LuqueCenter for Infectious Diseases-Parasitology, Heidelberg University Hospital, Heidelberg, Germany. thomson-luque@sumaya-biotech.com.ORCID http://orcid.org/0000-0001-8378-9497
Heidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radical control of malaria likely requires a vaccine that targets both the asymptomatic liver stages and the disease-causing blood stages of the human malaria parasite Plasmodium falciparum. While substantial progress has been made towards liver stage vaccines, the development of a blood stage vaccine is lagging behind. We have recently conducted a first-in-human clinical trial to evaluate the safety and immunogenicity of the recombinant, full-length merozoite surface protein 1 (MSP1

Identifiers

PMID37558673
PMCPMC10412566
OpenAlexW4385701556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.