Evidence map›Paper›PMID 37558570›Full record

ReviewTrends in immunology2023

Factors contributing to the potency of CD8

Yuri Sykulev

Open access · greenAbstract readReview
In one paragraph

Review in Trends in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  12. T-cell subsets inClinical & translational immunology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Yuri SykulevDepartment of Microbiology and Immunology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA; Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address: yuri.sykulev@jefferson.edu.
Thomas Jefferson University · US

Funding

Viral control mechanisms of HIV-specific T cells in HIV-infected lymph nodeR01AI118694 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI BETTS, MICHAEL R · 2015 to 2019
$3.3M
Role of immune receptor clustering in controlling efficacy of antibody-dependent FcγRIIIa-mediated cytotoxicity by NK cellsU01AI148117 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI CAMPBELL, KERRY S, SYKULEV, YURI · 2020 to 2024
$2.5M
Defining optimal TCR-pMHC interactions: implication for designing new T-cell based therapeutics to treat viral infections and cancerR01CA217714 · NCI · THOMAS JEFFERSON UNIVERSITY · PI SYKULEV, YURI · 2017 to 2019
$468k
NCI NIH HHS R01 CA217714NIAID NIH HHS R01 AI118694NIAID NIH HHS U01 AI148117
6 · The paper itself

Abstract

CD8

Indexed as

CD8-Positive T-LymphocytesT-Lymphocytes, CytotoxicCD8 AntigensHumansKiller Cells, NaturalReceptors, Antigen, T-CellCD8 AntigensReceptors, Antigen, T-CellCAR T cellsCD8 and CD4 co-receptorsCD8 and CD4 T cellsefficiency of cytolytic activitykinetics of target cell destructionTCR and co-receptors clustering

Identifiers

PMID37558570
PMCPMC10511257
OpenAlexW4385632453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.