Evidence map›Paper›PMID 37558097›Full record

ArticleInternational journal of radiation oncology, biology, physics2024

Proton and Electron Ultrahigh-Dose-Rate Isodose Irradiations Produce Differences in Reactive Oxygen Species Yields.

William Thomas, Jacob Sunnerberg, Matthew Reed, David J Gladstone, Rongxiao Zhang, Joseph Harms, Harold M Swartz, Brian W Pogue

Open access · greenAbstract read
In one paragraph

Article in International journal of radiation oncology, biology, physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
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  5. Microenvironmental remodeling in FLASH radiotherapy.Frontiers in cell and developmental biology · 2026
    Review
  6. Article
  7. Article
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  13. Review
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  16. Mechanisms of the FLASH effect: current insights and advances.Frontiers in cell and developmental biology · 2025
    Review
  17. Review
  18. Article
  19. Article
  20. Clinical and translational radiation oncology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

William ThomasDepartment of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin.
Jacob SunnerbergThayer School of Engineering, Dartmouth College, Hanover, New Hampshire.
Matthew ReedDepartment of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin.
David J GladstoneThayer School of Engineering, Dartmouth College, Hanover, New Hampshire; Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.
Rongxiao ZhangThayer School of Engineering, Dartmouth College, Hanover, New Hampshire; Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.
Joseph HarmsDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama.
Harold M SwartzThayer School of Engineering, Dartmouth College, Hanover, New Hampshire; Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.
Brian W PogueDepartment of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire. Electronic address: bpogue@wisc.edu.
Dartmouth College · USUniversity of Wisconsin–Madison · USUniversity of Alabama at Birmingham · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
Optimization of MeV FLASH radiotherapy for normal tissue preservationU01CA260446 · NCI · DARTMOUTH COLLEGE · PI David J. Gladstone, Jack Hoopes · 2022 to 2026
$3.1M
Oxygen Dynamics in FLASH RadiotherapyR01CA271330 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Brian William Pogue, Sergei Vinogradov · 2023 to 2026
$2.1M
Oxygen imaging by phosphorescence quenchingU24EB028941 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI VINOGRADOV, SERGEI · 2019 to 2023
$1.6M
NCI NIH HHS P30 CA014520NCI NIH HHS P30 CA023108NCI NIH HHS R01 CA271330NCI NIH HHS U01 CA260446NIBIB NIH HHS U24 EB028941
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ProtonsProton TherapyElectronsHumansRadiotherapy DosageReactive Oxygen SpeciesProtonsReactive Oxygen Species

Identifiers

PMID37558097
PMCPMC10843497
OpenAlexW4385621405

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.