Evidence map›Paper›PMID 37557062›Full record

ArticleInternational journal of hygiene and environmental health2023

Urinary Amino-PAHs in relation to diesel engine emissions and urinary mutagenicity.

Junfeng Jim Zhang, Yuxin Zheng, Roel Vermeulen, Xing Lucy Liu, Yufei Dai, Wei Hu, Linchen He, Yan Lin, Dianzhi Ren, Huawei Duan and 15 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of hygiene and environmental health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 8 institutions in 4 countries.

Junfeng Jim ZhangNicholas School of the Environment and Duke Global Health Institute, Duke University, Durham, NC, USA; Duke Kunshan University, Kunshan City, Jiangsu Province, China. Electronic address: junfeng.zhang@duke.edu.
Yuxin ZhengSchool of Public Health, Qingdao University, China.
Roel VermeulenUniversity of Utrecht, the Netherlands.
Xing Lucy LiuNicholas School of the Environment and Duke Global Health Institute, Duke University, Durham, NC, USA.
Yufei DaiKey Laboratory of Chemical Safety and Health, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Wei HuDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Linchen HeNicholas School of the Environment and Duke Global Health Institute, Duke University, Durham, NC, USA; College of Health, Lehigh University, Bethlehem, PA, USA.
Yan LinNicholas School of the Environment and Duke Global Health Institute, Duke University, Durham, NC, USA.
Dianzhi RenChaoyang Center for Disease Control and Prevention, Chaoyang, China.
Huawei DuanKey Laboratory of Chemical Safety and Health, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Yong NiuKey Laboratory of Chemical Safety and Health, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Jun XuHong Kong University, Hong Kong.
Wei FuChaoyang Center for Disease Control and Prevention, Chaoyang, China.
Kees MeliefsteUniversity of Utrecht, the Netherlands.
Baosen ZhouChina Medical University, Shenyang, China.
Jufang YangChaoyang Center for Disease Control and Prevention, Chaoyang, China.
Meng YeKey Laboratory of Chemical Safety and Health, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Xiaowei JiaKey Laboratory of Chemical Safety and Health, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Tao MengKey Laboratory of Chemical Safety and Health, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Ping BinKey Laboratory of Chemical Safety and Health, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Bryan A BassigDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
H Dean HosgoodDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA; Division of Epidemiology, Albert Einstein College of Medicine, New York, USA.
Debra SilvermanDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Qing LanDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Nathaniel RothmanDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
National Institute for Occupational Health and Poison Control · CNNational Cancer Institute · USDuke University · USBeijing Chaoyang Emergency Medical Center · CNUtrecht University · NLChina Medical University · CNQingdao University · CNUniversity of Hong Kong · HK

Funding

Occupational Exposure AssessmentZIACP010122 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI FRIESEN, MELISSA · 2009 to 2025
$8.6M
Intramural NIH HHS ZIA CP010122
6 · The paper itself

Abstract

Diesel exhaust has long been of health concern due to established toxicity including carcinogenicity in humans. However, the precise components of diesel engine emissions that drive carcinogenesis are still unclear. Limited work has suggested that nitrated polycyclic aromatic hydrocarbons (NPAHs) such as 1-nitropyrene and 2-nitrofluorene may be more abundant in diesel exhaust. The present study aimed to examine whether urinary amino metabolites of these NPAHs were associated with high levels of diesel engine emissions and urinary mutagenicity in a group of highly exposed workers including both smokers and nonsmokers. Spot urine samples were collected immediately following a standard work shift from each of the 54 diesel engine testers and 55 non-tester controls for the analysis of five amino metabolites of NPAHs, and cotinine (a biomarker of tobacco smoke exposure) using liquid chromatography-mass spectrometry. An overnight urine sample was collected in a subgroup of non-smoking participants for mutagenicity analysis using strain YG1041 in the Salmonella (Ames) mutagenicity assay. Personal exposure to fine particles (PM

Indexed as

MutagensPolycyclic Aromatic HydrocarbonsBiomarkersFluorenesHumansNitratesPyrenesSootVehicle Emissions1-aminopyrene2-aminofluoreneBiomarkersFluorenesMutagensNitratesPolycyclic Aromatic HydrocarbonsPyrenesSootVehicle EmissionsAmino-PAHsBiomonitoringCigarette smokingDiesel exhaustInhalation exposureNitro-PAHs

Identifiers

PMID37557062
PMCPMC10529049
OpenAlexW4385623100

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.